The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Large-Scale and Automated DNA Sequence Determination
Abstract
DNA sequence analysis is a multistage process that includes the preparation of DNA, its fragmentation and base analysis, and the interpretation of the resulting sequence information. New technological advances have led to the automation of certain steps in this process and have raised the possibility of large-scale DNA sequencing efforts in the near future [for example, 1 million base pairs (Mb) per year]. New sequencing methodologies, fully automated instrumentation, and improvements in sequencing-related computational resources may render genome-size sequencing projects (100 Mb or larger) feasible during the next 5 to 10 years.
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Citations
Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A., & Arnheim, N. (1985) · Science · doi:10.1126/science.2999980 · Cited by 8,956
Electrospray Ionization for Mass Spectrometry of Large Biomolecules
Fenn, J. B., Mann, M., Meng, C. K., Wong, S. F., & Whitehouse, C. M. (1989) · Science · doi:10.1126/science.2675315 · Cited by 7,634
Cited by
Next-generation DNA sequencing
Shendure, J., & Ji, H. (2008) · Nature Biotechnology · doi:10.1038/nbt1486 · Cited by 4,509
The sequence of sequencers: The history of sequencing DNA
Heather, J. M., & Chain, B. (2016) · Genomics · doi:10.1016/j.ygeno.2015.11.003 · Cited by 1,397
“Both of these improvements contributed to the development of increasingly automated DNA sequencing machines [27,28,29,30,31,32,33], and subsequently the first crop of commercial DNA sequencing machines [34] which were used to sequence the genomes of increasingly complex species.”
BackgroundNewman, T., de Bruijn, F. J., Green, P., Keegstra, K., Kende, H., McIntosh, L., Ohlrogge, J., Raikhel, N., Somerville, S., Thomashow, M., et al. (1994) · Plant Physiology · doi:10.1104/pp.106.4.1241 · Cited by 632
Southern, E. M., Maskos, U., & Elder, J. K. (1992) · Genomics · doi:10.1016/0888-7543(92)90014-j · Cited by 377
De novo assembly of short sequence reads
Paszkiewicz, K., & Studholme, D. J. (2010) · Briefings in Bioinformatics · doi:10.1093/bib/bbq020 · Cited by 204
Metadata
- Authors
- Hunkapiller, T., Kaiser, R. J., Koop, B. F., & Hood, L.
- Venue
- Science
- Published
- 1991-10-04
- Volume
- 254
- Issue
- 5028
- Pages
- 59-67
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2001321345
- Cited by
- 361
- References
- 3
- FWCI
- 7.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hunkapiller, T., Kaiser, R. J., Koop, B. F., & Hood, L. (1991). Large-Scale and Automated DNA Sequence Determination. Science. https://doi.org/10.1126/science.1925562
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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