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Cited by 535

The DOI matches its Crossref record.

Expression of Interleukin-10 Activity by Epstein-Barr Virus Protein BCRF1

Hsu, Di-Hwei, Malefyt, Rene de Waal, Fiorentino, David F., Dang, Minh-Ngoc, Vieira, Paulo, deVries, Jan, Spits, Hergen, Mosmann, Timothy R., Moore, Kevin W.·1990·Science
DOI 10.1126/science.2173142
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Abstract

Cytokine synthesis inhibitory factor (CSIF; interleukin-10), a product of mouse TH 2 T cell clones that inhibits synthesis of cytokines by mouse TH 1 T cell clones, exhibits extensive sequence similarity to an uncharacterized open reading frame in the Epstein-Barr virus BCRF1. Recombinant BCRF1 protein mimics the activity of interleukin-10, suggesting that BCRF1 may have a role in the interaction of the virus with the host's immune system.

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Metadata

Authors
Hsu, D.-H., Malefyt, R. D. W., Fiorentino, D. F., Dang, M.-N., Vieira, P., deVries, J., Spits, H., Mosmann, T. R., & Moore, K. W.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
1990-11-09
Volume
250
Issue
4982
Pages
830-832
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.2173142
OpenAlex
W2047999732
Cited by
535
References
0
FWCI
12.04
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Expression of Interleukin-10 Activity by Epstein-Barr Virus Protein BCRF1. https://app.cochat.ai/papers/10.1126/science.2173142
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Hsu, D.-H., Malefyt, R. D. W., Fiorentino, D. F., Dang, M.-N., Vieira, P., deVries, J., Spits, H., Mosmann, T. R., & Moore, K. W. (1990). Expression of Interleukin-10 Activity by Epstein-Barr Virus Protein BCRF1. Science. https://doi.org/10.1126/science.2173142

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.