The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Voltage-Sensitive Calcium Channels in Normal and Transformed 3T3 Fibroblasts
Abstract
Patch clamp recordings of whole-cell and single channel currents revealed the presence of two voltage-sensitive calcium channel types in the membrane of 3T3 fibroblasts. The two calcium channel types were identified by their unitary properties and pharmacological sensitivities. Both calcium channel types were present in all control 3T3 cells, but one type was selectively suppressed in 3T3 cells that had been transformed by activated c-H- ras , EJ- ras , v- fms , or polyoma middle T oncogenes. The presence of voltage-sensitive calcium channels in these nonexcitable cells and the control of their functional expression by transforming oncogenes raises questions about their role in the control of calcium-sensitive processes such as cell motility, cytoskeletal organization, and cell growth.
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Cites
Mechanism of activation of a human oncogene
Tabin, C. J., Bradley, S. M., Bargmann, C. I., Weinberg, R. A., Papageorge, A. G., Scolnick, E. M., Dhar, R., Lowy, D. R., & Chang, E. H. (1982) · Nature · doi:10.1038/300143a0 · Cited by 1,393
Cited by
Multiple types of neuronal calcium channels and their selective modulation
Tsien, R. W., Lipscombe, D., Madison, D. V., Bley, K. R., & Fox, A. P. (1988) · Trends in Neurosciences · doi:10.1016/0166-2236(88)90194-4 · Cited by 1,381
Block of Stretch-Activated Ion Channels in Xenopus Oocytes by Gadolinium and Calcium Ions
Yang, X.-C., & Sachs, F. (1989) · Science · doi:10.1126/science.2466333 · Cited by 803
Potassium channels and regulation of proliferation of human melanoma cells.
Nilius, B., & Wohlrab, W. (1992) · The Journal of Physiology · doi:10.1113/jphysiol.1992.sp018938 · Cited by 203
Metadata
- Authors
- Chen, C., Corbley, M. J., Roberts, T. M., & Hess, P.
- Venue
- Science
- Published
- 1988-02-26
- Volume
- 239
- Issue
- 4843
- Pages
- 1024-1026
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2045673068
- Cited by
- 180
- References
- 1
- FWCI
- 8.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chen, C., Corbley, M. J., Roberts, T. M., & Hess, P. (1988). Voltage-Sensitive Calcium Channels in Normal and Transformed 3T3 Fibroblasts. Science. https://doi.org/10.1126/science.2449730
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