Cited by 1,381Ion channel regulation and functionNeuroscience and Neuropharmacology ResearchCardiac electrophysiology and arrhythmias

Multiple types of neuronal calcium channels and their selective modulation

Tsien, R.W., Lipscombe, D., Madison, D.V., Bley, K.R., Fox, A.P.·1988·Trends in Neurosciences

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Crossref · 10.1016/0166-2236(88)90194-4

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80 of 80 references verified0 citation errors · 0 not checkable

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  • During synaptic activity, transient Ca2+ influx affects glutamate receptor trafficking, cytoskeletal remodeling, and local protein synthesis through activation of kinases, phosphatases, and transcription factors PGC-1α and CREB.

    “During synaptic activity, the transient Ca2+ influx affects glutamate receptor trafficking, cytoskeletal remodeling, and local protein synthesis through activation of cytosolic kinases, phosphatases, and the major neuronal transcription factors, including PGC-1α and cyclic AMP response element-binding protein (CREB) (Mattson and Arumugam, 2018; Tsien et al., 1988).”

    From NAD+ in Brain Aging and Neurodegenerative Disorders (2019) · cites this paper as Tsien et al., 1988

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Authors
Tsien, R. W., Lipscombe, D., Madison, D. V., Bley, K. R., & Fox, A. P.
Affiliations
Yale University (US)
Venue
Trends in Neurosciences
Publisher
Elsevier BV
Published
1988-01
Volume
11
Issue
10
Pages
431-438
ISSN
0166-2236 (ISSN-L)
OpenAlex
W2068617048
Cited by
1,381
References
80
Citations by year
2026: 4 · 2025: 3 · 2024: 11 · 2023: 8 · 2022: 13 · 2021: 11 · 2020: 10 · 2019: 15 · 2018: 9 · 2017: 9 · 2016: 11 · 2015: 19 · 2014: 19 · 2013: 16 · 2012: 14
FWCI
12.88
Type
journal article
Language
en
Open access
closed
Locations
  • Trends in Neurosciences (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords
voltage-gated calcium channels, calcium channel subtypes, channel gating, ionic conductance, channel pharmacology, calcium channel modulation, neurochemical regulation
MeSH terms
Action Potentials, Animals, Membrane Potentials, Neurons, Calcium Channels

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