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Epidemiology of Drug Resistance: Implications for a Post—Antimicrobial Era
Abstract
In the last several years, the frequency and spectrum of antimicrobial-resistant infections have increased in both the hospital and the community. Certain infections that are essentially untreatable have begun to occur as epidemics both in the developing world and in institutional settings in the United States. The increasing frequency of drug resistance has been attributed to combinations of microbial characteristics, selective pressures of antimicrobial use, and societal and technologic changes that enhance the transmission of drug-resistant organisms. Antimicrobial resistance is resulting in increased morbidity, mortality, and health-care costs. Prevention and control of these infections will require new antimicrobial agents, prudent use of existing agents, new vaccines, and enhanced public health efforts to reduce transmission.
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Citations
Cited by
Ibrahim, E. H., Sherman, G., Ward, S., Fraser, V. J., & Kollef, M. H. (2000) · Chest · doi:10.1378/chest.118.1.146 · Cited by 1,779
Gonzales, R. (1997) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1997.03550110039033 · Cited by 717
Roberts, M. C. (1996) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1996.tb00251.x · Cited by 689
Trends in Infectious Diseases Mortality in the United States
Pinner, R. W. (1996) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1996.03530270029027 · Cited by 487
Essential Oils, A New Horizon in Combating Bacterial Antibiotic Resistance
Yap, P. S. X., Yiap, B. C., Ping, H. C., & Lim, S. H. E. (2014) · The Open Microbiology Journal · doi:10.2174/1874285801408010006 · Cited by 426
Metadata
- Authors
- Cohen, M. L.
- Venue
- Science
- Published
- 1992-08-21
- Volume
- 257
- Issue
- 5073
- Pages
- 1050-1055
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2038014125
- Cited by
- 1,304
- References
- 0
- FWCI
- 58.76
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cohen, M. L. (1992). Epidemiology of Drug Resistance: Implications for a Post—Antimicrobial Era. Science. https://doi.org/10.1126/science.257.5073.1050
Data sources
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
