Cited by 426Essential Oils and Antimicrobial ActivityAntimicrobial agents and applicationsAntibiotic Resistance in Bacteria

Essential Oils, A New Horizon in Combating Bacterial Antibiotic Resistance

Open access
Yap, Polly Soo Xi, Yiap, Beow Chin, Ping, Hu Cai, Lim, Swee Hua Erin·2014·The Open Microbiology Journal

Abstract

For many years, the battle between humans and the multitudes of infection and disease causing pathogens continues. Emerging at the battlefield as some of the most significant challenges to human health are bacterial resistance and its rapid rise. These have become a major concern in global public health invigorating the need for new antimicrobial compounds. A rational approach to deal with antibiotic resistance problems requires detailed knowledge of the different biological and non-biological factors that affect the rate and extent of resistance development. Combination therapy combining conventional antibiotics and essential oils is currently blooming and represents a potential area for future investigations. This new generation of phytopharmaceuticals may shed light on the development of new pharmacological regimes in combating antibiotic resistance. This review consolidated and described the observed synergistic outcome between essential oils and antibiotics, and highlighted the possibilities of essential oils as the potential resistance modifying agent.

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  • Essential oils have demonstrated efficacy against multidrug-resistant/antibiotic-resistant bacteria.

    “Besides, they have demonstrated their efficacy against multidrug-resistant/antibiotic-resistant bacteria [38,39].”

    From Essential Oils as Antimicrobials in Crop Protection (2021) · cites this paper as [39]

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1 of the 88 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

  1. [42]Guerra FQ Mendes JM Sousa JP Increasing antibiotic activity against a multidrug-resistant Acinetobacter spp by essential oils of Citrus limon and Cinnamomum zeylanicum. Nat Prod Res 2011 22191514
  2. [45]Jacoby GA Munoz-Price LS The new beta-lactamases. N Engl J Med 2005 352 380 91 15673804
  3. [48]Cox SD Mann CM Markham JL The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil). J Appl Microbiol 2000 88 1 170 5 10735256
  4. [61]McGraw-Hill Higher Education (Firm).Annual editions. Microbiology. Annual editions. Dubuque. Iowa: McGraw-Hill Higher Education p v

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Authors
Yap, P. S. X., Yiap, B. C., Ping, H. C., & Lim, S. H. E.
Affiliations
IMU University (MY)
Corresponding author
Lim, Swee Hua Erin
Venue
The Open Microbiology Journal
Published
2014-02-07
Volume
8
Issue
1
Pages
6-14
ISSN
1874-2858 (ISSN-L)
OpenAlex
W2133763626
Cited by
426
References
88
Citations by year
2026: 20 · 2025: 40 · 2024: 50 · 2023: 39 · 2022: 48 · 2021: 51 · 2020: 43 · 2019: 43 · 2018: 31 · 2017: 29 · 2016: 16 · 2015: 12 · 2014: 3
FWCI
28.67
Type
journal article
Language
en
Open access
Locations
  • The Open Microbiology Journal (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
  • Physical Sciences › Chemistry › Organic Chemistry › Antimicrobial agents and applications
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
Keywords
essential oils, antibiotic resistance, bacterial resistance, antimicrobial synergy, combination therapy, herbal medicine, resistance-modifying agents, antimicrobial agents

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