Trends in Infectious Diseases Mortality in the United States
Abstract
Objective To evaluate recent trends in infectious diseases mortality in the United States. Design Descriptive study of infectious disease mortality, classifying International Classification of Diseases, Ninth Revision codes as infectious diseases, consequence of infectious diseases, or not infectious diseases. Multiple cause-of-death tapes from the National Center for Health Statistics for the years 1980 through 1992 were used, with a focus on underlying cause-of-death data and on codes that exclusively represent infectious diseases. Setting United States. Subjects All persons who died between 1980 and 1992. Main outcome measure Death. Results Between 1980 and 1992, the death rate due to infectious diseases as the underlying cause of death increased 58%, from 41 to 65 deaths per 100,000 population in the United States. Age-adjusted mortality from infectious diseases increased 39% during the same period. Infectious diseases mortality increased 25% among those aged 65 years and older (from 271 to 338 per 100,000), and 6.3 times among 25- to 44-year-olds (from six to 38 deaths per 100,000). Mortality due to respiratory tract infections increased 20%, from 25 to 30 deaths per 100,000, deaths attributed to human immunodeficiency virus increased from virtually none to 13 per 100,000 in 1992, and the rate of death due to septicemia increased 83% from 4.2 to 7.7 per 100,000. Conclusions Despite historical predictions that infectious diseases would wane in the United States, these dat…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Cited by
Sorted by citations
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene
Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631 · see citing works
Foodborne illness acquired in the United States—Major pathogens
Scallan, E., Hoekstra, R. M., Angulo, F. J., Tauxe, R. V., Widdowson, M.-A., Roy, S. L., Jones, J. L., & Griffin, P. M. (2011) · Emerging Infectious Diseases · doi:10.3201/eid1701.p11101 · Cited by 7,657 · see citing works
Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction
Chow, J. C., Young, D. W., Golenbock, D. T., Christ, W. J., & Gusovsky, F. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.16.10689 · Cited by 1,924 · see citing works
Trends in antimicrobial drug development: Implications for the future
Spellberg, B., Powers, J. H., Brass, E. P., Miller, L. G., & Edwards, J. E. (2004) · Clinical Infectious Diseases · doi:10.1086/420937 · Cited by 867 · see citing works
Godbout, J. P., Chen, J., Abraham, J., Richwine, A. F., Berg, B. M., Kelley, K. W., & Johnson, R. W. (2005) · The FASEB Journal · doi:10.1096/fj.05-3776fje · Cited by 813 · see citing works
Trends in Mortality Due to Invasive Mycotic Diseases in the United States, 1980–1997
McNeil, M. M., Nash, S. L., Hajjeh, R. A., Phelan, M. A., Conn, L. A., Plikaytis, B. D., & Warnock, D. W. (2001) · Clinical Infectious Diseases · doi:10.1086/322606 · Cited by 657 · see citing works
Tay, T. L., Savage, J. C., Hui, C. W., Bisht, K., & Tremblay, M. (2017) · The Journal of Physiology · doi:10.1113/jp272134 · Cited by 562 · see citing works
Morgan, J., Meltzer, M. I., Plikaytis, B. D., Sofair, A. N., Huie-White, S., Wilcox, S., Harrison, L. H., Seaberg, E. C., Hajjeh, R. A., & Teutsch, S. M. (2005) · Infection Control & Hospital Epidemiology · doi:10.1086/502581 · Cited by 437 · see citing works
Sanlioglu, S., Williams, C. M., Samavati, L., Butler, N. S., Wang, G., McCray, P. B., Ritchie, T. C., Hunninghake, G. W., Zandi, E., & Engelhardt, J. F. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102061200 · Cited by 395 · see citing works
Age-Associated Defect in Human TLR-1/2 Function
van Duin, D., Mohanty, S., Thomas, V., Ginter, S., Montgomery, R. R., Fikrig, E., Allore, H. G., Medzhitov, R., & Shaw, A. C. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.2.970 · Cited by 352 · see citing works
Epidemiology of Human Metapneumovirus
Kahn, J. S. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00014-06 · Cited by 355 · see citing works
The Impact of Candidemia on Length of Hospital Stay, Outcome, and Overall Cost of Illness
Rentz, A. M., Halpern, M. T., & Bowden, R. (1998) · Clinical Infectious Diseases · doi:10.1086/514955 · Cited by 310 · see citing works
Li, Q., & Engelhardt, J. F. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511153200 · Cited by 219 · see citing works
Burden of aspergillosis-related hospitalizations in the United States
Dasbach, E. J., Davies, G. M., & Teutsch, S. M. (2000) · Clinical Infectious Diseases · doi:10.1086/317487 · Cited by 159 · see citing works
Evolution of Drug Resistance in <i>Candida Albicans</i>
Cowen, L. E., Anderson, J. B., & Kohn, L. M. (2002) · Annual Review of Microbiology · doi:10.1146/annurev.micro.56.012302.160907 · Cited by 151 · see citing works
Pfaller, M. A., Messer, S. A., Houston, A., Rangel-Frausto, M. S., Wiblin, T., Blumberg, H. M., Edwards, J. E., Jarvis, W., Martin, M. A., Neu, H. C., et al. (1998) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/s0732-8893(97)00245-9 · Cited by 141 · see citing works
Takakura, S. (2004) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkh053 · Cited by 117 · see citing works
Cellular immunity and memory to respiratory virus infections
Woodland, D. L., Hogan, R. J., & Zhong, W. (2001) · Immunologic Research · doi:10.1385/ir:24:1:53 · Cited by 97 · see citing works
Mizgerd, J. P., Lupa, M. M., Kogan, M. S., Warren, H. B., Kobzik, L., & Topulos, G. P. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200303-412oc · Cited by 66 · see citing works
- Authors
- Pinner, R. W.
- Affiliations
- National Center for Infectious Diseases (US)
- Corresponding author
- Pinner, Robert W.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1996-01-17
- Volume
- 275
- Issue
- 3
- Pages
- 189
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2092009189
- Cited by
- 487
- References
- 0
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 5 · 2022: 5 · 2021: 5 · 2020: 6 · 2019: 14 · 2018: 6 · 2017: 8 · 2016: 11 · 2015: 15 · 2014: 25 · 2013: 21 · 2012: 16
- FWCI
- 93.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Health Information Management › Global Health and Epidemiology
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Social Sciences › Demography › Insurance, Mortality, Demography, Risk Management
- Keywords
- infectious disease mortality, mortality trends, age-adjusted mortality, respiratory infections, HIV mortality, septicemia, older adults, United States
- MeSH terms
- Adolescent, Adult, Aged, Cause of Death, Child, Child, Preschool, Communicable Diseases, Female, Humans, Infant, Male, Middle Aged, Mortality, United States, Age Distribution, Sex Distribution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
