The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Purification, Cloning, and Expression of Ciliary Neurotrophic Factor (CNTF)
Abstract
Ciliary neurotrophic factor (CNTF) is one of a small number of proteins with neurotrophic activities distinct from nerve growth factor (NGF). CNTF has now been purified and cloned and the primary structure of CNTF from rabbit sciatic nerve has been determined. Biologically active CNTF has been transiently expressed from a rabbit complementary DNA clone. CNTF is a neural effector without significant sequence homologies to any previously reported protein.
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Cites
DNA sequencing with chain-terminating inhibitors
Sanger, F., Nicklen, S., & Coulson, A. R. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.12.5463 · Cited by 68,572
Towbin, H., Staehelin, T., & Gordon, J. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.9.4350 · Cited by 53,385
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Feinberg, A. P., & Vogelstein, B. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90418-9 · Cited by 24,887
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Antibodies, a laboratory manual
(1989) · Biomedicine & Pharmacotherapy · doi:10.1016/0753-3322(89)90130-3 · Cited by 12,366
A simple and very efficient method for generating cDNA libraries
Gubler, U., & Hoffman, B. J. (1983) · Gene · doi:10.1016/0378-1119(83)90230-5 · Cited by 4,510
Ribonucleic acid isolated by cesium chloride centrifugation
Glisin, V., Crkvenjakov, R., & Byus, C. (1974) · Biochemistry · doi:10.1021/bi00709a025 · Cited by 2,156
Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences
Ullrich, A., Shine, J., Chirgwin, J., Pictet, R., Tischer, E., Rutter, W. J., & Goodman, H. M. (1977) · Science · doi:10.1126/science.325648 · Cited by 1,238
A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
BOSHART, M., WEBER, F., JAHN, G., DORSCHHLER, K., FLECKENSTEIN, B., & SCHAFFNER, W. (1985) · Cell · doi:10.1016/s0092-8674(85)80025-8 · Cited by 1,140
Abraham, J. A., Mergia, A., Whang, J. L., Tumolo, A., Friedman, J., Hjerrild, K. A., Gospodarowicz, D., & Fiddes, J. C. (1986) · Science · doi:10.1126/science.2425435 · Cited by 1,015
Cited by
Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF
Maisonpierre, P. C., Belluscio, L., Squinto, S., Ip, N. Y., Furth, M. E., Lindsay, R. M., & Yancopoulos, G. D. (1990) · Science · doi:10.1126/science.2321006 · Cited by 1,322
The changing scene of neurotrophic factors
Thoenen, H. (1991) · Trends in Neurosciences · doi:10.1016/0166-2236(91)90097-e · Cited by 820
Interleukin 6 and its receptor: ten years later
Hirano, T. (1998) · International Reviews of Immunology · doi:10.3109/08830189809042997 · Cited by 788
Neurotrophic factors: from molecule to man
Lindsay, R. M., Wiegand, S. J., Anthony Altar, C., & DiStefano, P. S. (1994) · Trends in Neurosciences · doi:10.1016/0166-2236(94)90099-x · Cited by 788
Mignatti, P., Morimoto, T., & Rifkin, D. B. (1992) · Journal of Cellular Physiology · doi:10.1002/jcp.1041510113 · Cited by 451
Metadata
- Authors
- Lin, L.-F. H., Mismer, D., Lile, J. D., Armes, L. G., Butler, E. T., Vannice, J. L., & Collins, F.
- Venue
- Science
- Published
- 1989-11-24
- Volume
- 246
- Issue
- 4933
- Pages
- 1023-1025
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2057835832
- Cited by
- 417
- References
- 26
- FWCI
- 14.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Purification, Cloning, and Expression of Ciliary Neurotrophic Factor (CNTF). https://app.cochat.ai/papers/10.1126/science.2587985
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- Lin, L.-F. H., Mismer, D., Lile, J. D., Armes, L. G., Butler, E. T., Vannice, J. L., & Collins, F. (1989). Purification, Cloning, and Expression of Ciliary Neurotrophic Factor (CNTF). Science. https://doi.org/10.1126/science.2587985
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.