The DOI matches its Crossref record.
Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences
Abstract
Recombinant bacterial plasmids have been constructed that contain complementary DNA prepared from rat islets of Langerhans messenger RNA. Three plasmids contain cloned sequences representing the complete coding region of rat proinsulin I, part of the preproinsulin I prepeptide, and the untranslated 3′ terminal region of the mRNA. A fourth plasmid contains sequences derived from the A chain region of rat preproinsulin II.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,725
Self-citationThe discovery of receptor tyrosine kinases: targets for cancer therapy
Gschwind, A., Fischer, O. M., & Ullrich, A. (2004) · Nature Reviews Cancer · doi:10.1038/nrc1360 · Cited by 1,227
Self-citationActivation of a novel human transforming gene, ret, by DNA rearrangement
Takahashi, M., Ritz, J., & Cooper, G. M. (1985) · Cell · doi:10.1016/0092-8674(85)90115-1 · Cited by 854
Expression in Escherichia coli of a Chemically Synthesized Gene for the Hormone Somatostatin
Itakura, K., Hirose, T., Crea, R., Riggs, A. D., Heyneker, H. L., Bolivar, F., & Boyer, H. W. (1977) · Science · doi:10.1126/science.412251 · Cited by 853
Base sequence studies of 300 nucleotide renatured repeated human DNA clones
Deininger, P. L., Jolly, D. J., Rubin, C. M., Friedmann, T., & Schmid, C. W. (1981) · Journal of Molecular Biology · doi:10.1016/0022-2836(81)90219-9 · Cited by 586
Metadata
- Authors
- Ullrich, A., Shine, J., Chirgwin, J., Pictet, R., Tischer, E., Rutter, W. J., & Goodman, H. M.
- Venue
- Science
- Published
- 1977-06-17
- Volume
- 196
- Issue
- 4296
- Pages
- 1313-1319
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2084106399
- Cited by
- 1,238
- References
- 0
- FWCI
- 159.35
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences. https://app.cochat.ai/papers/10.1126/science.325648
- The paper
- Ullrich, A., Shine, J., Chirgwin, J., Pictet, R., Tischer, E., Rutter, W. J., & Goodman, H. M. (1977). Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences. Science. https://doi.org/10.1126/science.325648
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
