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Activation by Attention of the Human Reticular Formation and Thalamic Intralaminar Nuclei

Kinomura, Shigeo, Larsson, Jonas, Gulyás, Balázs, Roland, Per E.·1996·Science

Abstract

It has been known for over 45 years that electrical stimulation of the midbrain reticular formation and of the thalamic intralaminar nuclei of the brain alerts animals. However, lesions of these sectors fail to impair arousal and vigilance in some cases, making the role of the ascending activating reticular system controversial. Here, a positron emission tomographic study showed activation of the midbrain reticular formation and of thalamic intralaminar nuclei when human participants went from a relaxed awake state to an attention-demanding reaction-time task. These results confirm the role of these areas of the brain and brainstem in arousal and vigilance.

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Metadata

Authors
Kinomura, S., Larsson, J., Gulyás, B., & Roland, P. E.
Venue
Science
Published
1996-01-26
Volume
271
Issue
5248
Pages
512-515
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2020694953
Cited by
705
References
2
FWCI
15.09
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Activation by Attention of the Human Reticular Formation and Thalamic Intralaminar Nuclei. https://app.cochat.ai/papers/10.1126/science.271.5248.512
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Kinomura, S., Larsson, J., Gulyás, B., & Roland, P. E. (1996). Activation by Attention of the Human Reticular Formation and Thalamic Intralaminar Nuclei. Science. https://doi.org/10.1126/science.271.5248.512

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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