The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Population Dynamics of Immune Responses to Persistent Viruses
Abstract
Mathematical models, which are based on a firm understanding of biological interactions, can provide nonintuitive insights into the dynamics of host responses to infectious agents and can suggest new avenues for experimentation. Here, a simple mathematical approach is developed to explore the relation between antiviral immune responses, virus load, and virus diversity. The model results are compared to data on cytotoxic T cell responses and viral diversity in infections with the human T cell leukemia virus (HTLV-1) and the human immunodeficiency virus (HIV-1).
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Citations
Cites
A principle of natural self-organization: Part A: Emergence of the hypercycle
Eigen, M., & Schuster, P. (1977) · Naturwissenschaften · doi:10.1007/bf00450633 · Cited by 1,752
Cited by
Virus dynamics and drug therapy
Bonhoeffer, S., May, R. M., Shaw, G. M., & Nowak, M. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.13.6971 · Cited by 632
Self-citationJeffery, K. J. M., Usuku, K., Hall, S. E., Matsumoto, W., Taylor, G. P., Procter, J., Bunce, M., Ogg, G. S., Welsh, K. I., Weber, J. N., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3848 · Cited by 419
Self-citationNowak, M. A., Lloyd, A. L., Vasquez, G. M., Wiltrout, T. A., Wahl, L. M., Bischofberger, N., Williams, J., Kinter, A., Fauci, A. S., Hirsch, V. M., et al. (1997) · Journal of Virology · doi:10.1128/jvi.71.10.7518-7525.1997 · Cited by 284
Self-citationBiphasic clearance kinetics of hepatitis B virus from patients during adefovir dipivoxil therapy
Tsiang, M., Rooney, J. F., Toole, J. J., & Gibbs, C. S. (1999) · Hepatology · doi:10.1002/hep.510290626 · Cited by 242
Mode of onset of type 2 diabetes from normal or impaired glucose tolerance
Ferrannini, E., Nannipieri, M., Williams, K., Gonzales, C., Haffner, S. M., & Stern, M. P. (2004) · Diabetes · doi:10.2337/diabetes.53.1.160 · Cited by 153
Metadata
- Authors
- Nowak, M. A., & Bangham, C. R. M.
- Venue
- Science
- Published
- 1996-04-05
- Volume
- 272
- Issue
- 5258
- Pages
- 74-79
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1980587508
- Cited by
- 1,277
- References
- 1
- FWCI
- 41.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nowak, M. A., & Bangham, C. R. M. (1996). Population Dynamics of Immune Responses to Persistent Viruses. Science. https://doi.org/10.1126/science.272.5258.74
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
