The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Presynaptic Long-Term Depression at the Hippocampal Mossy Fiber—CA3 Synapse
Abstract
Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength may underlie learning and memory in the brain. The induction of LTP occurs in postsynaptic cells in the hippocampal CA1 region but is presynaptic in CA3. LTD is also well characterized in CA1 but not in CA3. Low-frequency stimulation of mouse hippocampal slices caused homosynaptic LTD at the mossy fiber-CA3 synapse, which may be induced presynaptically by activation of metabotropic glutamate receptors. Thus, the efficacy of mossy fiber-CA3 synapses can be regulated bidirectionally, which may contribute to neuronal information processing.
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Citations
Cites
A family of metabotropic glutamate receptors
Tanabe, Y., Masu, M., Ishii, T., Shigemoto, R., & Nakanishi, S. (1992) · Neuron · doi:10.1016/0896-6273(92)90118-w · Cited by 940
Comparison of Two Forms of Long-Term Potentiation in Single Hippocampal Neurons
Zalutsky, R. A., & Nicoll, R. A. (1990) · Science · doi:10.1126/science.2114039 · Cited by 759
Kutsuwada, T., Sakimura, K., Manabe, T., Takayama, C., Katakura, N., Kushiya, E., Natsume, R., Watanabe, M., Inoue, Y., Yagi, T., et al. (1996) · Neuron · doi:10.1016/s0896-6273(00)80051-3 · Cited by 498
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Cited by
Glutamate receptors in the mammalian central nervous system
Ozawa, S., Kamiya, H., & Tsuzuki, K. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00085-3 · Cited by 1,122
Cellular and Synaptic Adaptations Mediating Opioid Dependence
Williams, J. T., Christie, M. J., & Manzoni, O. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.299 · Cited by 848
Synaptic plasticity at hippocampal mossy fibre synapses
Nicoll, R. A., & Schmitz, D. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1786 · Cited by 653
Reiner, A., & Levitz, J. (2018) · Neuron · doi:10.1016/j.neuron.2018.05.018 · Cited by 631
Presynaptic Calcium Current Modulation by a Metabotropic Glutamate Receptor
Takahashi, T., Forsythe, I. D., Tsujimoto, T., Barnes-Davies, M., & Onodera, K. (1996) · Science · doi:10.1126/science.274.5287.594 · Cited by 392
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Metadata
- Authors
- Kobayashi, K., Manabe, T., & Takahashi, T.
- Venue
- Science
- Published
- 1996-08-02
- Volume
- 273
- Issue
- 5275
- Pages
- 648-650
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1972057413
- Cited by
- 159
- References
- 3
- FWCI
- 3.77
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kobayashi, K., Manabe, T., & Takahashi, T. (1996). Presynaptic Long-Term Depression at the Hippocampal Mossy Fiber—CA3 Synapse. Science. https://doi.org/10.1126/science.273.5275.648
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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