The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
DCP-1, a Drosophila Cell Death Protease Essential for Development
Abstract
Apoptosis, a form of cellular suicide, involves the activation of CED-3-related cysteine proteases (caspases). The regulation of caspases by apoptotic signals and the precise mechanism by which they kill the cell remain unknown. In Drosophila , different death-inducing stimuli induce the expression of the apoptotic activator reaper . Cell killing by reaper and two genetically linked apoptotic activators, hid and grim , requires caspase activity. A Drosophila caspase, named Drosophila caspase-1 (DCP-1), was identified and found to be structurally and biochemically similar to Caenorhabditis elegans CED-3. Loss of zygotic DCP-1 function in Drosophila caused larval lethality and melanotic tumors, showing that this gene is essential for normal development.
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Cites
Apoptosis in the Pathogenesis and Treatment of Disease
Thompson, C. B. (1995) · Science · doi:10.1126/science.7878464 · Cited by 6,524
Cited by
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
Earnshaw, W. C., Martins, L. M., & Kaufmann, S. H. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.383 · Cited by 2,760
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015) · Cell Death & Differentiation · doi:10.1038/cdd.2014.137 · Cited by 1,002
Ryoo, H. D., Gorenc, T., & Steller, H. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.08.019 · Cited by 624
Self-citationRodriguez, A., Oliver, H., Zou, H., Chen, P., Wang, X., & Abrams, J. M. (1999) · Nature Cell Biology · doi:10.1038/12984 · Cited by 332
Hou, Y.-C. C., Chittaranjan, S., Barbosa, S. G., McCall, K., & Gorski, S. M. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200712091 · Cited by 180
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Metadata
- Authors
- Song, Z., McCall, K., & Steller, H.
- Venue
- Science
- Published
- 1997-01-24
- Volume
- 275
- Issue
- 5299
- Pages
- 536-540
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2014988811
- Cited by
- 332
- References
- 1
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- Song, Z., McCall, K., & Steller, H. (1997). DCP-1, a Drosophila Cell Death Protease Essential for Development. Science. https://doi.org/10.1126/science.275.5299.536
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
