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Cited by 489

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Immunoglobulin E Production in the Absence of Interleukin-4-Secreting CD1-Dependent Cells

Smiley, Stephen T., Kaplan, Mark H., Grusby, Michael J.·1997·Science

Abstract

A lymphocyte population that expresses surface markers found on T cells and natural killer (NK) cells secretes large amounts of interleukin-4 (IL-4) immediately after T cell receptor ligation. These NK-like T cells are thus thought to be important for the initiation of type 2 T helper cell (T H 2) responses. CD1-deficient mice were found to lack this lymphocyte subset, but they could nevertheless mount a protypical T H 2 response; after immunization with antibody to immunoglobulin D (IgD), CD1-deficient mice produced IgE. Thus, although dependent on CD1 for their development, IL-4-secreting NK-like T cells are not required for T H 2 responses.

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Crossref · 10.1126/science.275.5302.977

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Metadata

Authors
Smiley, S. T., Kaplan, M. H., & Grusby, M. J.
Venue
Science
Published
1997-02-14
Volume
275
Issue
5302
Pages
977-979
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2044306159
Cited by
489
References
2
FWCI
20.70
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Immunoglobulin E Production in the Absence of Interleukin-4-Secreting CD1-Dependent Cells. https://app.cochat.ai/papers/10.1126/science.275.5302.977
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Smiley, S. T., Kaplan, M. H., & Grusby, M. J. (1997). Immunoglobulin E Production in the Absence of Interleukin-4-Secreting CD1-Dependent Cells. Science. https://doi.org/10.1126/science.275.5302.977

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.