The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Bacterial Interference Caused by Autoinducing Peptide Variants
Abstract
The synthesis of virulence factors and other extracellular proteins by Staphylococcus aureus is globally controlled by the agr locus, which encodes a two-component signaling pathway whose activating ligand is an agr -encoded autoinducing peptide. The cognate peptides produced by some strains inhibit the expression of agr in other strains, and the amino acid sequences of peptide and receptor are markedly different between such strains, suggesting a hypervariability-generating mechanism. Cross-inhibition of gene expression represents a type of bacterial interference that could be correlated with the ability of one strain to exclude others from infection or colonization sites, or both.
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Citations
Cites
Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers.
Hillenkamp, F., Karas, M., Beavis, R. C., & Chait, B. T. (1991) · Analytical Chemistry · doi:10.1021/ac00024a716 · Cited by 1,930
Self-citation
Cited by
Pathogenicity and virulence of Staphylococcus aureus
Cheung, G. Y. C., Bae, J. S., & Otto, M. (2021) · Virulence · doi:10.1080/21505594.2021.1878688 · Cited by 1,380
Biofilm Dispersal: Mechanisms, Clinical Implications, and Potential Therapeutic Uses
Kaplan, J. B. (2010) · Journal of Dental Research · doi:10.1177/0022034509359403 · Cited by 949
The microbiome in patients with atopic dermatitis
Paller, A. S., Kong, H. H., Seed, P., Naik, S., Scharschmidt, T. C., Gallo, R. L., Luger, T., & Irvine, A. D. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.11.015 · Cited by 525
Impact of the agr Quorum‐Sensing System on Adherence to Polystyrene in Staphylococcus aureus
Vuong, C., Saenz, H. L., Götz, F., & Otto, M. (2000) · The Journal of Infectious Diseases · doi:10.1086/317606 · Cited by 499
Microbiota-mediated colonization resistance: mechanisms and regulation
Caballero-Flores, G., Pickard, J. M., & Núñez, G. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00833-7 · Cited by 474
Metadata
- Authors
- Ji, G., Beavis, R., & Novick, R. P.
- Venue
- Science
- Published
- 1997-06-27
- Volume
- 276
- Issue
- 5321
- Pages
- 2027-2030
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2088970163
- Cited by
- 817
- References
- 1
- FWCI
- 7.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ji, G., Beavis, R., & Novick, R. P. (1997). Bacterial Interference Caused by Autoinducing Peptide Variants. Science. https://doi.org/10.1126/science.276.5321.2027
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
