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Cited by 1,380

The DOI matches its Crossref record; 275 of the 275 references it cites were found in a registry or an index.

Pathogenicity and virulence of Staphylococcus aureus

Open access
Cheung, Gordon Y. C., Bae, Justin S., Otto, Michael·2021·Virulence

Abstract

Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and mortality due to an infectious agent. This pathogen can cause a wide variety of diseases, ranging from moderately severe skin infections to fatal pneumonia and sepsis. Treatment of S. aureus infections is complicated by antibiotic resistance and a working vaccine is not available. There has been ongoing and increasing interest in the extraordinarily high number of toxins and other virulence determinants that S. aureus produces and how they impact disease. In this review, we will give an overview of how S. aureus initiates and maintains infection and discuss the main determinants involved. A more in-depth understanding of the function and contribution of S. aureus virulence determinants to S. aureus infection will enable us to develop anti-virulence strategies to counteract the lack of an anti-S. aureus vaccine and the ever-increasing shortage of working antibiotics against this important pathogen.

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Crossref · 10.1080/21505594.2021.1878688

Cites

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Citations

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Metadata

Authors
Cheung, G. Y. C., Bae, J. S., & Otto, M.
Venue
Virulence
Published
2021-01-31
Volume
12
Issue
1
Pages
547-569
ISSN
  • 2150-5594 (ISSN-L)
  • 2150-5608
OpenAlex
W3126393518
Cited by
1,380
References
275
FWCI
57.90
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Pathogenicity and virulence of Staphylococcus aureus. https://app.cochat.ai/papers/10.1080/21505594.2021.1878688
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Cheung, G. Y. C., Bae, J. S., & Otto, M. (2021). Pathogenicity and virulence of Staphylococcus aureus. Virulence. https://doi.org/10.1080/21505594.2021.1878688

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.