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Cited by 7,452

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The Complete Genome Sequence of Escherichia coli K-12

Blattner, Frederick R., Plunkett, Guy, Bloch, Craig A., Perna, Nicole T., Burland, Valerie, Riley, Monica, Collado-Vides, Julio, Glasner, Jeremy D., Rode, Christopher K., Mayhew, George F., Gregor, Jason, Davis, Nelson Wayne, Kirkpatrick, Heather A., Goeden, Michael A., Rose, Debra J., Mau, Bob, Shao, Ying·1997·Science

Abstract

The 4,639,221–base pair sequence of Escherichia coli K-12 is presented. Of 4288 protein-coding genes annotated, 38 percent have no attributed function. Comparison with five other sequenced microbes reveals ubiquitous as well as narrowly distributed gene families; many families of similar genes within E. coli are also evident. The largest family of paralogous proteins contains 80 ABC transporters. The genome as a whole is strikingly organized with respect to the local direction of replication; guanines, oligonucleotides possibly related to replication and recombination, and most genes are so oriented. The genome also contains insertion sequence (IS) elements, phage remnants, and many other patches of unusual composition indicating genome plasticity through horizontal transfer.

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Crossref · 10.1126/science.277.5331.1453

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Metadata

Authors
Blattner, F. R., Plunkett, G., Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., & Shao, Y.
Venue
Science
Published
1997-09-05
Volume
277
Issue
5331
Pages
1453-1462
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2134153749
Cited by
7,452
References
2
FWCI
126.90
Type
journal article
Language
en
Open access
closed

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.