The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Functional Expression of a Mammalian Odorant Receptor
Abstract
Candidate mammalian odorant receptors were first cloned some 6 years ago. The physiological function of these receptors in initiating transduction in olfactory receptor neurons remains to be established. Here, a recombinant adenovirus was used to drive expression of a particular receptor gene in an increased number of sensory neurons in the rat olfactory epithelium. Electrophysiological recording showed that increased expression of a single gene led to greater sensitivity to a small subset of odorants.
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Citations
Cites
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
Buck, L., & Axel, R. (1991) · Cell · doi:10.1016/0092-8674(91)90418-x · Cited by 4,987
Cited by
Combinatorial Receptor Codes for Odors
Malnic, B., Hirono, J., Sato, T., & Buck, L. B. (1999) · Cell · doi:10.1016/s0092-8674(00)80581-4 · Cited by 2,316
A Novel Family of Divergent Seven-Transmembrane Proteins
Clyne, P. J., Warr, C. G., Freeman, M. R., Lessing, D., Kim, J., & Carlson, J. R. (1999) · Neuron · doi:10.1016/s0896-6273(00)81093-4 · Cited by 1,155
Identification of Ligands for Olfactory Receptors by Functional Expression of a Receptor Library
Krautwurst, D., Yau, K.-W., & Reed, R. R. (1998) · Cell · doi:10.1016/s0092-8674(00)81716-x · Cited by 606
The Molecular Architecture of Odor and Pheromone Sensing in Mammals
Buck, L. B. (2000) · Cell · doi:10.1016/s0092-8674(00)80698-4 · Cited by 477
TRP2: A candidate transduction channel for mammalian pheromone sensory signaling
Liman, E. R., Corey, D. P., & Dulac, C. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.10.5791 · Cited by 447
Metadata
- Authors
- Zhao, H., Ivic, L., Otaki, J. M., Hashimoto, M., Mikoshiba, K., & Firestein, S.
- Venue
- Science
- Published
- 1998-01-09
- Volume
- 279
- Issue
- 5348
- Pages
- 237-242
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2011120951
- Cited by
- 624
- References
- 1
- FWCI
- 30.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhao, H., Ivic, L., Otaki, J. M., Hashimoto, M., Mikoshiba, K., & Firestein, S. (1998). Functional Expression of a Mammalian Odorant Receptor. Science. https://doi.org/10.1126/science.279.5348.237
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
