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Cited by 279

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Association of Malaria Parasite Population Structure, HLA, and Immunological Antagonism

Gilbert, Sarah C., Plebanski, Magdalena, Gupta, Sunetra, Morris, Joanne, Cox, Martin, Aidoo, Michael, Kwiatkowski, Dominic, Greenwood, Brian M., Whittle, Hilton C., Hill, Adrian V. S.·1998·Science

Abstract

Host-parasite coevolution has been likened to a molecular arms race, with particular parasite genes evolving to evade specific host defenses. Study of the variants of an antigenic epitope of Plasmodium falciparum that induces a cytotoxic T cell response supports this view. In African children with malaria, the variants present are influenced by the presence of a human leukocyte antigen (HLA) type that restricts the immune response to this epitope. The distribution of parasite variants may be further influenced by the ability of cohabiting parasite strains to facilitate each other's survival by down-regulating cellular immune responses, using altered peptide ligand antagonism.

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Crossref · 10.1126/science.279.5354.1173

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Metadata

Authors
Gilbert, S. C., Plebanski, M., Gupta, S., Morris, J., Cox, M., Aidoo, M., Kwiatkowski, D., Greenwood, B. M., Whittle, H. C., & Hill, A. V. S.
Venue
Science
Published
1998-02-20
Volume
279
Issue
5354
Pages
1173-1177
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1988952151
Cited by
279
References
15
FWCI
39.93
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Association of Malaria Parasite Population Structure, HLA, and Immunological Antagonism. https://app.cochat.ai/papers/10.1126/science.279.5354.1173
The paper
Gilbert, S. C., Plebanski, M., Gupta, S., Morris, J., Cox, M., Aidoo, M., Kwiatkowski, D., Greenwood, B. M., Whittle, H. C., & Hill, A. V. S. (1998). Association of Malaria Parasite Population Structure, HLA, and Immunological Antagonism. Science. https://doi.org/10.1126/science.279.5354.1173

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.