The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Association of Malaria Parasite Population Structure, HLA, and Immunological Antagonism
Abstract
Host-parasite coevolution has been likened to a molecular arms race, with particular parasite genes evolving to evade specific host defenses. Study of the variants of an antigenic epitope of Plasmodium falciparum that induces a cytotoxic T cell response supports this view. In African children with malaria, the variants present are influenced by the presence of a human leukocyte antigen (HLA) type that restricts the immune response to this epitope. The distribution of parasite variants may be further influenced by the ability of cohabiting parasite strains to facilitate each other's survival by down-regulating cellular immune responses, using altered peptide ligand antagonism.
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Citations
Cites
Common West African HLA antigens are associated with protection from severe malaria
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Self-citationMating Patterns in Malaria Parasite Populations of Papua New Guinea
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Cited by
World Health Organization (2000) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(00)90300-6 · Cited by 1,085
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Biological and biomedical implications of the co-evolution of pathogens and their hosts
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Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells
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Self-citationGenetics of susceptibitlity to human infectious disease
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Self-citation
Metadata
- Authors
- Gilbert, S. C., Plebanski, M., Gupta, S., Morris, J., Cox, M., Aidoo, M., Kwiatkowski, D., Greenwood, B. M., Whittle, H. C., & Hill, A. V. S.
- Venue
- Science
- Published
- 1998-02-20
- Volume
- 279
- Issue
- 5354
- Pages
- 1173-1177
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1988952151
- Cited by
- 279
- References
- 15
- FWCI
- 39.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Association of Malaria Parasite Population Structure, HLA, and Immunological Antagonism. https://app.cochat.ai/papers/10.1126/science.279.5354.1173
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- Gilbert, S. C., Plebanski, M., Gupta, S., Morris, J., Cox, M., Aidoo, M., Kwiatkowski, D., Greenwood, B. M., Whittle, H. C., & Hill, A. V. S. (1998). Association of Malaria Parasite Population Structure, HLA, and Immunological Antagonism. Science. https://doi.org/10.1126/science.279.5354.1173
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.