The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Rapid Turnover of T Lymphocytes in SIV-Infected Rhesus Macaques
Abstract
Studies of lymphocyte turnover in animal models have implications for understanding the mechanism of cell killing and the extent of lymphocyte regeneration in human immunodeficiency virus infection. Quantitative analyses of the sequential changes in bromodeoxyuridine labeling of CD4 and CD8 T lymphocytes not only revealed the normal proliferation and death rates of these cell populations in uninfected macaques, but also showed a substantial increase in these rates associated with simian immunodeficiency virus (SIV) infection. Faster labeling and delabeling in memory and naı̈ve T lymphocyte subpopulations as well as in NK (natural killer) and B cells were also observed in infected macaques, suggesting a state of generalized activation induced by SIV.
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Cites
Efron, B., & Tibshirani, R. (1986) · Statistical Science · doi:10.1214/ss/1177013815 · Cited by 6,033
Turnover of naive- and memory-phenotype T cells.
Tough, D. F., & Sprent, J. (1994) · The Journal of experimental medicine · doi:10.1084/jem.179.4.1127 · Cited by 869
T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4 + T Cell Turnover
Wolthers, K. C., Bea, G., Wisman, A., Otto, S. A., de Roda Husman, A.-M., Schaft, N., de Wolf, F., Goudsmit, J., Coutinho, R. A., van der Zee, A. G. J., et al. (1996) · Science · doi:10.1126/science.274.5292.1543 · Cited by 286
Palmer, L. D., Weng, N.-P., Levine, B. L., June, C. H., Lane, H. C., & Hodes, R. J. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.7.1381 · Cited by 129
Cited by
Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans
Hellerstein, M., Hanley, M. B., Cesar, D., Siler, S., Papageorgopoulos, C., Wieder, E., Schmidt, D., Hoh, R., Neese, R., Macallan, D., et al. (1999) · Nature Medicine · doi:10.1038/4772 · Cited by 593
Development and Homeostasis of T Cell Memory in Rhesus Macaque
Pitcher, C. J., Hagen, S. I., Walker, J. M., Lum, R., Mitchell, B. L., Maino, V. C., Axthelm, M. K., & Picker, L. J. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.1.29 · Cited by 467
HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T-cells
Oswald-Richter, K., Grill, S. M., Shariat, N., Leelawong, M., Sundrud, M. S., Haas, D. W., & Unutmaz, D. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020198 · Cited by 301
Haynes, L., Eaton, S. M., Burns, E. M., Randall, T. D., & Swain, S. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2433717100 · Cited by 270
Metadata
- Authors
- Mohri, H., Bonhoeffer, S., Monard, S., Perelson, A. S., & Ho, D. D.
- Venue
- Science
- Published
- 1998-02-20
- Volume
- 279
- Issue
- 5354
- Pages
- 1223-1227
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1994307941
- Cited by
- 366
- References
- 4
- FWCI
- 8.64
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mohri, H., Bonhoeffer, S., Monard, S., Perelson, A. S., & Ho, D. D. (1998). Rapid Turnover of T Lymphocytes in SIV-Infected Rhesus Macaques. Science. https://doi.org/10.1126/science.279.5354.1223
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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