The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off
Abstract
The immune system responds in a regulated fashion to microbes and eliminates them, but it does not respond to self-antigens. Several regulatory mechanisms function to terminate responses to foreign antigens, returning the immune system to a basal state after the antigen has been cleared, and to maintain unresponsiveness, or tolerance, to self-antigens. Here, recent advances in understanding of the molecular bases and physiologic roles of the mechanisms of immune homeostasis are examined.
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Citations
Cites
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Cited by
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187
Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function
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Kaech, S. M., Tan, J. T., Wherry, E. J., Konieczny, B. T., Surh, C. D., & Ahmed, R. (2003) · Nature Immunology · doi:10.1038/ni1009 · Cited by 1,830
Delves, P. J., & Roitt, I. M. (2000) · New England Journal of Medicine · doi:10.1056/nejm200007063430107 · Cited by 1,666
Blair, P. A., Noreña, L. Y., Flores-Borja, F., Rawlings, D. J., Isenberg, D. A., Ehrenstein, M. R., & Mauri, C. (2010) · Immunity · doi:10.1016/j.immuni.2009.11.009 · Cited by 1,574
Metadata
- Authors
- Parijs, L. V., & Abbas, A. K.
- Venue
- Science
- Published
- 1998-04-10
- Volume
- 280
- Issue
- 5361
- Pages
- 243-248
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2029599607
- Cited by
- 965
- References
- 45
- FWCI
- 33.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off. https://app.cochat.ai/papers/10.1126/science.280.5361.243
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- Parijs, L. V., & Abbas, A. K. (1998). Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off. Science. https://doi.org/10.1126/science.280.5361.243
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
