The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Interaction of Human Arp2/3 Complex and the Listeria monocytogenes ActA Protein in Actin Filament Nucleation
Abstract
Actin filament assembly at the cell surface of the pathogenic bacterium Listeria monocytogenes requires the bacterial ActA surface protein and the host cell Arp2/3 complex. Purified Arp2/3 complex accelerated the nucleation of actin polymerization in vitro, but pure ActA had no effect. However, when combined, the Arp2/3 complex and ActA synergistically stimulated the nucleation of actin filaments. This mechanism of activating the host Arp2/3 complex at the L. monocytogenes surface may be similar to the strategy used by cells to control Arp2/3 complex activity and hence the spatial and temporal distribution of actin polymerization.
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Cites
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Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes
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Cited by
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex
Machesky, L. M., Mullins, R. D., Higgs, H. N., Kaiser, D. A., Blanchoin, L., May, R. C., Hall, M. E., & Pollard, T. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3739 · Cited by 773
The actin cytoskeleton and actin-based motility
Svitkina, T. (2018) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018267 · Cited by 761
Takenawa, T., & Miki, H. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.10.1801 · Cited by 604
Higgs, H. N., & Pollard, T. D. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.6.1311 · Cited by 446
The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration
Suraneni, P., Rubinstein, B., Unruh, J. R., Durnin, M., Hanein, D., & Li, R. (2012) · Journal of Cell Biology · doi:10.1083/jcb.201112113 · Cited by 337
Metadata
- Authors
- Welch, M. D., Rosenblatt, J., Skoble, J., Portnoy, D. A., & Mitchison, T. J.
- Venue
- Science
- Published
- 1998-07-03
- Volume
- 281
- Issue
- 5373
- Pages
- 105-108
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2045923054
- Cited by
- 508
- References
- 31
- FWCI
- 17.90
- Type
- journal article
- Language
- en
- Open access
- closed
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- Welch, M. D., Rosenblatt, J., Skoble, J., Portnoy, D. A., & Mitchison, T. J. (1998). Interaction of Human Arp2/3 Complex and the Listeria monocytogenes ActA Protein in Actin Filament Nucleation. Science. https://doi.org/10.1126/science.281.5373.105
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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