The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Attenuation of Virulence by Disruption of the Mycobacterium tuberculosis erp Gene
Abstract
The virulence of the mycobacteria that cause tuberculosis depends on their ability to multiply in mammalian hosts. Disruption of the bacterial erp gene, which encodes the exported repetitive protein, impaired multiplication of M. tuberculosis and M. bovis Bacille Calmette-Guérin in cultured macrophages and mice. Reintroduction of erp into the mutants restored their ability to multiply. These results indicate that erp contributes to the virulence of M. tuberculosis .
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Cites
Sturgill-Koszycki, S., Schlesinger, P. H., Chakraborty, P., Haddix, P. L., Collins, H. L., Fok, A. K., Allen, R. D., Gluck, S. L., Heuser, J., & Russell, D. G. (1994) · Science · doi:10.1126/science.8303277 · Cited by 1,302
Cited by
Betts, J. C., Lukey, P. T., Robb, L. C., McAdam, R. A., & Duncan, K. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.02779.x · Cited by 1,395
Mycobacterium tuberculosis Pathogenesis and Molecular Determinants of Virulence
Smith, I. (2003) · Clinical Microbiology Reviews · doi:10.1128/cmr.16.3.463-496.2003 · Cited by 1,154
Pym, A. S., Brodin, P., Brosch, R., Huerre, M., & Cole, S. T. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03237.x · Cited by 729
Protein Kinase G from Pathogenic Mycobacteria Promotes Survival Within Macrophages
Walburger, A., Koul, A., Ferrari, G., Nguyen, L., Prescianotto-Baschong, C., Huygen, K., Klebl, B., Thompson, C., Bacher, G., & Pieters, J. (2004) · Science · doi:10.1126/science.1099384 · Cited by 595
Parish, T., & Stoker, N. G. (2000) · Microbiology · doi:10.1099/00221287-146-8-1969 · Cited by 512
Metadata
- Authors
- Berthet, F.-X., Lagranderie, M., Gounon, P., Laurent-Winter, C., Ensergueix, D., Chavarot, P., Thouron, F., Maranghi, E., Pelicic, V., Portnoı̈, D., Marchal, G., & Gicquel, B.
- Venue
- Science
- Published
- 1998-10-23
- Volume
- 282
- Issue
- 5389
- Pages
- 759-762
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2164160871
- Cited by
- 203
- References
- 1
- FWCI
- 14.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Attenuation of Virulence by Disruption of the Mycobacterium tuberculosis erp Gene. https://app.cochat.ai/papers/10.1126/science.282.5389.759
- The paper
- Berthet, F.-X., Lagranderie, M., Gounon, P., Laurent-Winter, C., Ensergueix, D., Chavarot, P., Thouron, F., Maranghi, E., Pelicic, V., Portnoı̈, D., Marchal, G., & Gicquel, B. (1998). Attenuation of Virulence by Disruption of the Mycobacterium tuberculosis erp Gene. Science. https://doi.org/10.1126/science.282.5389.759
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
