The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
A Computational Screen for Methylation Guide snoRNAs in Yeast
Abstract
Small nucleolar RNAs (snoRNAs) are required for ribose 2′-O-methylation of eukaryotic ribosomal RNA. Many of the genes for this snoRNA family have remained unidentified in Saccharomyces cerevisiae , despite the availability of a complete genome sequence. Probabilistic modeling methods akin to those used in speech recognition and computational linguistics were used to computationally screen the yeast genome and identify 22 methylation guide snoRNAs, snR50 to snR71. Gene disruptions and other experimental characterization confirmed their methylation guide function. In total, 51 of the 55 ribose methylated sites in yeast ribosomal RNA were assigned to 41 different guide snoRNAs.
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Cited by
The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs
Schattner, P., Brooks, A. N., & Lowe, T. M. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki366 · Cited by 2,295
Self-citationThe genome of the cucumber,Cucumis sativus L
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The microRNAs of Caenorhabditis elegans
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Metadata
- Authors
- Lowe, T. M., & Eddy, S. R.
- Venue
- Science
- Published
- 1999-02-19
- Volume
- 283
- Issue
- 5405
- Pages
- 1168-1171
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2058044724
- Cited by
- 465
- References
- 30
- FWCI
- 7.83
- Type
- journal article
- Language
- en
- Open access
- closed
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