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Microfabrication Inside Capillaries Using Multiphase Laminar Flow Patterning
Abstract
The reaction of species in solutions flowing laminarly (without turbulent mixing) inside capillaries was used as the basis for a broadly applicable method of microfabrication. In this method, patterning occurs as a result of transport of reactive species to interfaces within the capillary by laminar flow. A wide range of chemistries can be used to generate structures with feature sizes of less than 5 micrometers and with spatial localization to within 5 micrometers. The method is applicable to the patterning of metals, organic polymers, inorganic crystals, and ceramics on the inner walls of preformed capillaries, using both additive and subtractive processes.
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Cited by
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Hermanson, K. D., Lumsdon, S. O., Williams, J. P., Kaler, E. W., & Velev, O. D. (2001) · Science · doi:10.1126/science.1063821 · Cited by 561
Microfluidic tectonics: A comprehensive construction platform for microfluidic systems
Beebe, D. J., Moore, J. S., Yu, Q., Liu, R. H., Kraft, M. L., Jo, B.-H., & Devadoss, C. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.250273097 · Cited by 353
Tokeshi, M., Minagawa, T., Uchiyama, K., Hibara, A., Sato, K., Hisamoto, H., & Kitamori, T. (2002) · Analytical Chemistry · doi:10.1021/ac011111z · Cited by 342
Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery
Vladisavljević, G. T., Khalid, N., Neves, M. A., Kuroiwa, T., Nakajima, M., Uemura, K., Ichikawa, S., & Kobayashi, I. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.07.017 · Cited by 313
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Metadata
- Authors
- Kenis, P. J. A., Ismagilov, R. F., & Whitesides, G. M.
- Venue
- Science
- Published
- 1999-07-02
- Volume
- 285
- Issue
- 5424
- Pages
- 83-85
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2017581879
- Cited by
- 659
- References
- 0
- FWCI
- 26.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kenis, P. J. A., Ismagilov, R. F., & Whitesides, G. M. (1999). Microfabrication Inside Capillaries Using Multiphase Laminar Flow Patterning. Science. https://doi.org/10.1126/science.285.5424.83
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.