The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
TAF-Containing and TAF-Independent Forms of Transcriptionally Active TBP in Vivo
Abstract
Transcriptional activity in yeast strongly correlates with promoter occupancy by general factors such as TATA binding protein (TBP), TFIIA, and TFIIB, but not with occupancy by TBP-associated factors (TAFs). Thus, TBP exists in at least two transcriptionally active forms in vivo. The TAF-containing form corresponds to the TFIID complex, whereas the form lacking TAFs corresponds to TBP itself or to some other TBP complex. Heat shock treatment altered the relative utilization of these TBP forms, with TFIID being favored. Promoter-specific variations in the association of these distinct forms of TBP may explain why only some yeast genes require TFIID for transcriptional activity in vivo.
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Cites
A Role for Transcriptional Repressors in Targeting the Yeast Swi/Snf Complex
Dimova, D., Nackerdien, Z., Furgeson, S., Eguchi, S., & Osley, M. A. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80189-6 · Cited by 105
Cited by
Phenotypic Consequences of Promoter-Mediated Transcriptional Noise
Blake, W. J., Balázsi, G., Kohanski, M. A., Isaacs, F. J., Murphy, K. F., Kuang, Y., Cantor, C. R., Walt, D. R., & Collins, J. J. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.11.003 · Cited by 629
Huisinga, K. L., & Pugh, B. F. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00087-5 · Cited by 560
Mason, P. B., & Struhl, K. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.22.8323-8333.2003 · Cited by 340
Self-citationExchange of RNA Polymerase II Initiation and Elongation Factors during Gene Expression In Vivo
Pokholok, D. K., Hannett, N. M., & Young, R. A. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00502-6 · Cited by 311
A Comprehensive Genomic Binding Map of Gene and Chromatin Regulatory Proteins in Saccharomyces
Venters, B. J., Wachi, S., Mavrich, T. N., Andersen, B. E., Jena, P., Sinnamon, A. J., Jain, P., Rolleri, N. S., Jiang, C., Hemeryck-Walsh, C., et al. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.01.015 · Cited by 294
Metadata
- Authors
- Kuras, L., Kosa, P., Mencia, M., & Struhl, K.
- Venue
- Science
- Published
- 2000-05-19
- Volume
- 288
- Issue
- 5469
- Pages
- 1244-1248
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2085428320
- Cited by
- 169
- References
- 1
- FWCI
- 7.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kuras, L., Kosa, P., Mencia, M., & Struhl, K. (2000). TAF-Containing and TAF-Independent Forms of Transcriptionally Active TBP in Vivo. Science. https://doi.org/10.1126/science.288.5469.1244
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