The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
A Comprehensive Genomic Binding Map of Gene and Chromatin Regulatory Proteins in Saccharomyces
Open accessAbstract
SUMMARY Hundreds of different proteins regulate and implement transcription in Saccharomyces. Yet their inter-relationships have not been investigated on a comprehensive scale. Here we determined the genome-wide binding locations of 200 transcription-related proteins, under normal and acute heat shock conditions. This study distinguishes binding between distal versus proximal promoter regions as well as the 3' ends of genes for nearly all mRNA and tRNA genes. This study reveals 1) a greater diversity and specialization of regulation associated with the SAGA transcription pathway compared to the TFIID pathway, 2) new regulators enriched at tRNA genes, 3) a global co-occupancy network of >20,000 unique regulator combinations that show a high degree of regulatory interconnections among lowly-expressed genes, 4) regulators of the SAGA pathway located largely distal to the core promoter and regulators of the TFIID pathway located proximally, and 5) distinct mobilization of SAGA- versus TFIID-linked regulators during acute heat shock.
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Metadata
- Authors
- Venters, B. J., Wachi, S., Mavrich, T. N., Andersen, B. E., Jena, P., Sinnamon, A. J., Jain, P., Rolleri, N. S., Jiang, C., Hemeryck-Walsh, C., & Pugh, B. F.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2011-02
- Volume
- 41
- Issue
- 4
- Pages
- 480-492
- ISSN
- 1097-2765 (ISSN-L)
- OpenAlex
- W2144688273
- Cited by
- 294
- References
- 57
- FWCI
- 11.64
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Venters, B. J., Wachi, S., Mavrich, T. N., Andersen, B. E., Jena, P., Sinnamon, A. J., Jain, P., Rolleri, N. S., Jiang, C., Hemeryck-Walsh, C., & Pugh, B. F. (2011). A Comprehensive Genomic Binding Map of Gene and Chromatin Regulatory Proteins in Saccharomyces. Molecular Cell. https://doi.org/10.1016/j.molcel.2011.01.015
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