The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Nimodipine Facilitates Associative Learning in Aging Rabbits
Abstract
Nimodipine is one of several dihydropyridines that block calcium channels. Originally administered to improve cerebral blood flow in elderly patients with chronic cerebrovascular disorders, nimodipine was noted to facilitate learning. These observations led to the present investigation of the effects of nimodipine on associative learning in aging rabbits. Nimodipine accelerated acquisition of conditioned eye-blink in both young and aging rabbits without altering the amplitude of responses to the conditioned or unconditioned stimuli or causing nonspecific responding. Thus, nimodipine may be a candidate for an effective treatment for age-related learning deficits.
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Cites
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Cited by
Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States
Mattson, M. P., & Arumugam, T. V. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.05.011 · Cited by 1,242
Impact of aging on hippocampal function: plasticity, network dynamics, and cognition
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Metadata
- Authors
- Deyo, R. A., Straube, K. T., & Disterhoft, J. F.
- Venue
- Science
- Published
- 1989-02-10
- Volume
- 243
- Issue
- 4892
- Pages
- 809-811
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1976116530
- Cited by
- 306
- References
- 13
- FWCI
- 13.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- Deyo, R. A., Straube, K. T., & Disterhoft, J. F. (1989). Nimodipine Facilitates Associative Learning in Aging Rabbits. Science. https://doi.org/10.1126/science.2916127
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
