The DOI matches its Crossref record.
Congenital Poisoning by Polychlorinated Biphenyls and Their Contaminants in Taiwan
Abstract
In 1979, a mass poisoning occurred in Taiwan from cooking oil contaminated by thermally degraded polychlorinated biphenyls. Because these chemicals persist in human tissue, children born to female patients after the outbreak were exposed in utero. In 1985, 117 children born to affected women and 108 unexposed controls were examined and evaluated. The exposed children were shorter and lighter than controls; they had abnormalities of gingiva, skin, nails, teeth, and lungs more frequently than did controls. The exposed children showed delay of developmental milestones, deficits on formal developmental testing, and abnormalities on behavioral assessment. These findings are most consistent with a generalized disorder of ectodermal tissue. This syndrome is one of very few documented to result from transplacental exposure to pollutant chemicals.
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Citations
Cited by
Intellectual impairment in children exposed to polychlorinated biphenyls in utero
Jacobson, J. L., & Jacobson, S. W. (1996) · New England Journal of Medicine · doi:10.1056/nejm199609123351104 · Cited by 1,132
Lithium-induced increase in human brain grey matter
Moore, G. J., Bebchuk, J. M., Wilds, I. B., Chen, G., & Menji, H. K. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02793-8 · Cited by 649
Effects of PCB exposure on neuropsychological function in children.
Schantz, S. L., Widholm, J. J., & Rice, D. C. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.5461 · Cited by 503
Høyer, B. B., Ramlau-Hansen, C. H., Pedersen, H. S., Góralczyk, K., Chumak, L., Jönsson, B. A., Bonde, J. P., & Toft, G. (2015) · BMC Public Health · doi:10.1186/s12889-015-1465-3 · Cited by 441
Gladen, B. C., Rogan, W. J., Hardy, P., Thullen, J., Tingelstad, J., & Tully, M. (1988) · The Journal of Pediatrics · doi:10.1016/s0022-3476(88)80569-9 · Cited by 344
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Metadata
- Authors
- Rogan, W. J., Gladen, B. C., Hung, K.-L., Koong, S.-L., Shih, L.-Y., Taylor, J. S., Wu, Y.-C., Yang, D., Ragan, N. B., & Hsu, C.-C.
- Venue
- Science
- Published
- 1988-07-15
- Volume
- 241
- Issue
- 4863
- Pages
- 334-336
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1985278934
- Cited by
- 543
- References
- 0
- FWCI
- 18.43
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rogan, W. J., Gladen, B. C., Hung, K.-L., Koong, S.-L., Shih, L.-Y., Taylor, J. S., Wu, Y.-C., Yang, D., Ragan, N. B., & Hsu, C.-C. (1988). Congenital Poisoning by Polychlorinated Biphenyls and Their Contaminants in Taiwan. Science. https://doi.org/10.1126/science.3133768
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
