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Cortical Flow in Animal Cells
Abstract
A concerted flow of actin filaments associated with the inner face of the plasma membrane may provide the basis for many animal cell movements. The flow is driven by gradients of tension in the cell cortex, which pull cortical components from regions of relaxation to regions of contraction. In some cases cortical components return through the cytoplasm to establish a continuous cycle. This cortically located motor may drive cell locomotion, growth cone migration, the capping of antigens on a lymphocyte surface, and cytokinesis.
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Citations
Cited by
Forscher, P., & Smith, S. J. (1988) · The Journal of cell biology · doi:10.1083/jcb.107.4.1505 · Cited by 854
Force Generation, Transmission, and Integration during Cell and Tissue Morphogenesis
Lecuit, T., Lenne, P.-F., & Munro, E. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100109-104027 · Cited by 621
Neuronal Cytomechanics: The Actin-Based Motility of Growth Cones
Smith, S. J. (1988) · Science · doi:10.1126/science.3055292 · Cited by 329
CHARRAS, G. T. (2008) · Journal of Microscopy · doi:10.1111/j.1365-2818.2008.02059.x · Cited by 320
Calcium Gradients Underlying Polarization and Chemotaxis of Eosinophils
Brundage, R. A., Fogarty, K. E., Tuft, R. A., & Fay, F. S. (1991) · Science · doi:10.1126/science.1948048 · Cited by 294
Metadata
- Authors
- Bray, D., & White, J. G.
- Venue
- Science
- Published
- 1988-02-19
- Volume
- 239
- Issue
- 4842
- Pages
- 883-888
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1998287390
- Cited by
- 574
- References
- 0
- FWCI
- 17.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bray, D., & White, J. G. (1988). Cortical Flow in Animal Cells. Science. https://doi.org/10.1126/science.3277283
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.