The DOI matches its Crossref record.
Is Pharma Running Out of Brainy Ideas?
Abstract
Recent cutbacks raise concerns about the future of drug development for nervous system disorders.
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Claims other papers make about this one
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In the citing paper
“It is possible to provide realistic estimates of power and to predict the number of new associations for each increment in sample size 128,129,140”
From Genetic architectures of psychiatric disorders: the emerging picture and its implications (2012) · cites this paper as [140]
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Toward the future of psychiatric diagnosis: the seven pillars of RDoC
Cuthbert, B. N., & Insel, T. R. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-126 · Cited by 3,053
Genetic architectures of psychiatric disorders: the emerging picture and its implications
Sullivan, P. F., Daly, M. J., & O'Donovan, M. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3240 · Cited by 1,177
Using Neuroscience to Help Understand Fear and Anxiety: A Two-System Framework
LeDoux, J. E., & Pine, D. S. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16030353 · Cited by 1,035
“The pharmaceutical industry has concluded that the probability of discovering new treatments is low (2, 110), and it has curtailed investment in future psychotropic medication discovery.”
BackgroundThe Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization
Hamley, I. W. (2012) · Chemical Reviews · doi:10.1021/cr3000994 · Cited by 892
Serotonin and brain function: a tale of two receptors
Carhart-Harris, R., & Nutt, D. (2017) · Journal of Psychopharmacology · doi:10.1177/0269881117725915 · Cited by 739
“For the brave new psychiatry of the future – that many would like to see (Miller, 2010) – decisions about whether to passively endure or actively address, may become increasingly pertinent.”
Background
Metadata
- Authors
- Miller, G.
- Corresponding author
- Miller, Greg
- Venue
- Science
- Published
- 2010-07-30
- Volume
- 329
- Issue
- 5991
- Pages
- 502-504
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2075757880
- Cited by
- 284
- References
- 0
- Citations by year
- 2026: 8 · 2025: 9 · 2024: 13 · 2023: 11 · 2022: 24 · 2021: 14 · 2020: 12 · 2019: 23 · 2018: 15 · 2017: 25 · 2016: 11 · 2015: 25 · 2014: 18 · 2013: 21 · 2012: 31
- Type
- other
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Pharmaceutical Economics and Policy
- Health Sciences › Nursing › Issues, ethics and legal aspects › Pharmaceutical industry and healthcare
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Keywords
- drug development, neurological disorders, pharmaceutical industry, research funding cuts, brain research, neuropharmacology
- MeSH terms
- Mental Disorders, Central Nervous System Agents, Central Nervous System Diseases, Clinical Trials as Topic, Drug Industry, Humans, Drug Approval, Access to Information, Biomedical Research, Drug Discovery, Public-Private Sector Partnerships
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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