The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Mechanism of the Rapid Effect of 17β-Estradiol on Medial Amygdala Neurons
Abstract
The mechanism by which sex steroids rapidly modulate the excitability of neurons was investigated by intracellular recording of neurons in rat medial amygdala brain slices. Brief hyperpolarization and increased potassium conductance were produced by 17β-estradiol. This effect persisted after elimination of synaptic input and after suppression of protein synthesis. Thus, 17β-estradiol directly changes the ionic conductance of the postsynaptic membrane of medial amygdala neurons. In addition, a greater proportion of the neurons from females than from males responded to 17β-estradiol.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Atlas of estradiol‐concentrating cells in the central nervous system of the female rat
Pfaff, D., & Keiner, M. (1973) · Journal of Comparative Neurology · doi:10.1002/cne.901510204 · Cited by 1,494
Towle, A. C., & Sze, P. Y. (1983) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(83)90079-1 · Cited by 351
Gonadal Steroids: Effects on Excitability of Hippocampal Pyramidal Cells
Teyler, T. J., Vardaris, R. M., Lewis, D., & Rawitch, A. B. (1980) · Science · doi:10.1126/science.7190730 · Cited by 315
Glucose responding neurons in the nucleus tractus solitarius of the rat: In vitro study
Mizuno, Y., & Oomura, Y. (1984) · Brain Research · doi:10.1016/0006-8993(84)90466-9 · Cited by 244
Self-citationKelly, M. J., Moss, R. L., & Dudley, C. A. (1976) · Brain Research · doi:10.1016/0006-8993(76)91017-9 · Cited by 170
Direct inhibition of tyrosine hydroxylase activity by catechol estrogens.
Lloyd, T., & Weisz, J. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34622-7 · Cited by 167
Kelly, M. J., Moss, R. L., Dudley, C. A., & Fawcett, C. P. (1977) · Experimental Brain Research · doi:10.1007/bf00237857 · Cited by 137
Nishizuka, M., & Arai, Y. (1981) · Brain Research · doi:10.1016/0006-8993(81)90247-x · Cited by 122
Autoradiographic Localization of Estradiol-Concentrating Cells in the Female Hamster Brain
Krieger, M. S., Morrell, J. I., & Pfaff, D. W. (2008) · Neuroendocrinology · doi:10.1159/000122626 · Cited by 115
Yagi, K. (1973) · Brain Research · doi:10.1016/0006-8993(73)90219-9 · Cited by 113
Cited by
Multiple Actions of Steroid Hormones—A Focus on Rapid, Nongenomic Effects
Falkenstein, E., Tillmann, H.-C., Christ, M., Feuring, M., & Wehling, M. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01468-6 · Cited by 991
Landys, M. M., Ramenofsky, M., & Wingfield, J. C. (2006) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2006.02.013 · Cited by 853
Sex, stress and the hippocampus: allostasis, allostatic load and the aging process
MCEWEN, B. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00027-1 · Cited by 753
Nongenomic steroid action: controversies, questions, and answers
LÖSEL, R. M., FALKENSTEIN, E., FEURING, M., SCHULTZ, A., TILLMANN, H.-C., ROSSOL-HASEROTH, K., & WEHLING, M. (2003) · Physiological Reviews · doi:10.1152/physrev.00003.2003 · Cited by 561
A corticosteroid receptor in neuronal membranes
Orchinik, M., Murray, T. F., & Moore, F. L. (1991) · Science · doi:10.1126/science.2063198 · Cited by 523
Metadata
- Authors
- Nabekura, J., Oomura, Y., Minami, T., Mizuno, Y., & Fukuda, A.
- Venue
- Science
- Published
- 1986-07-11
- Volume
- 233
- Issue
- 4760
- Pages
- 226-228
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2053141298
- Cited by
- 262
- References
- 21
- FWCI
- 4.12
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Mechanism of the Rapid Effect of 17β-Estradiol on Medial Amygdala Neurons. https://app.cochat.ai/papers/10.1126/science.3726531
- The paper
- Nabekura, J., Oomura, Y., Minami, T., Mizuno, Y., & Fukuda, A. (1986). Mechanism of the Rapid Effect of 17β-Estradiol on Medial Amygdala Neurons. Science. https://doi.org/10.1126/science.3726531
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
