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Cited by 375

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro

Nordan, Richard P., Potter, Michael·1986·Science
DOI 10.1126/science.3726549
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Abstract

Plasmacytoma (PCT) cell lines dependent for proliferation and survival on a factor elaborated by the murine macrophage cell line, P388D1, were established in vitro. Adherent peritoneal cells induced by pristane produced 50-fold greater amounts of this activity in vitro than did resident cells. The molecules responsible for plasmacytoma growth were distinct from a number of characterized factors including interleukin-1, -2, and -3, macrophage colony-stimulating factor, B-cell stimulatory factor-1, B-cell growth factor II, epidermal growth factor, transforming growth factor-β, and γ- and β-interferon, none of which were able to support the growth of the factor-dependent PCT cell lines. These results suggest that PCT growth factor may be a novel factor that has not been previously characterized and, further, that its production is associated with the pristane-induced, chronic peritoneal inflammatory response that precedes plasmacytoma formation.

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Metadata

Authors
Nordan, R. P., & Potter, M.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
1986-08
Volume
233
Issue
4763
Pages
566-569
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.3726549
OpenAlex
W2040020188
Cited by
375
References
22
FWCI
17.65
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro. https://app.cochat.ai/papers/10.1126/science.3726549
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Nordan, R. P., & Potter, M. (1986). A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro. Science. https://doi.org/10.1126/science.3726549

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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