The DOI matches its Crossref record.
Multiple, Distinct Forms of Bovine and Human Protein Kinase C Suggest Diversity in Cellular Signaling Pathways
Abstract
A new family of protein kinase C-related genes has been identified in bovine, human, and rat genomes. The alpha-, beta-, and gamma-type protein kinase sequences are highly homologous, include a kinase domain, and potential calcium-binding sites, and they contain interspersed variable regions. The corresponding genes are located on distinct human chromosomes; the possibility of even greater genetic complexity of this gene family is suggested by Northern and Southern hybridization analyses.
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Cited by
Clark, J. D., Lin, L.-L., Kriz, R. W., Ramesha, C. S., Sultzman, L. A., Lin, A. Y., Milona, N., & Knopf, J. L. (1991) · Cell · doi:10.1016/0092-8674(91)90556-e · Cited by 1,688
The extended protein kinase C superfamily
MELLOR, H., & PARKER, P. J. (1998) · Biochemical Journal · doi:10.1042/bj3320281 · Cited by 1,538
Self-citationA Retroviral Oncogene, akt , Encoding a Serine-Threonine Kinase Containing an SH2-Like Region
Bellacosa, A., Testa, J. R., Staal, S. P., & Tsichlis, P. N. (1991) · Science · doi:10.1126/science.1833819 · Cited by 939
The Complete Primary Structure of Protein Kinase C—the Major Phorbol Ester Receptor
Parker, P. J., Coussens, L., Totty, N., Rhee, L., Young, S., Chen, E., Stabel, S., Waterfield, M. D., & Ullrich, A. (1986) · Science · doi:10.1126/science.3755547 · Cited by 854
Self-citationDifferential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes
Peralta, E. G., Ashkenazi, A., Winslow, J. W., Ramachandran, J., & Capon, D. J. (1988) · Nature · doi:10.1038/334434a0 · Cited by 658
Metadata
- Authors
- Coussens, L., Parker, P. J., Rhee, L., Yang-Feng, T. L., Chen, E., Waterfield, M. D., Francke, U., & Ullrich, A.
- Venue
- Science
- Published
- 1986-08-22
- Volume
- 233
- Issue
- 4766
- Pages
- 859-866
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2054800842
- Cited by
- 1,042
- References
- 0
- FWCI
- 47.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Coussens, L., Parker, P. J., Rhee, L., Yang-Feng, T. L., Chen, E., Waterfield, M. D., Francke, U., & Ullrich, A. (1986). Multiple, Distinct Forms of Bovine and Human Protein Kinase C Suggest Diversity in Cellular Signaling Pathways. Science. https://doi.org/10.1126/science.3755548
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
