The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies
Abstract
Bovine brain-derived acidic fibroblast growth factor (aFGF) is a protein mitogen originally identified in partially purified preparations of whole brain. The protein was purified to homogeneity and shown to be a potent vascular endothelial cell mitogen in culture and angiogenic substance in vivo. The homology of aFGF to human interleukin-1β was inferred from partial sequence data. The complete amino acid sequence of aFGF has now been determined and observed to be similar to both basic FGF and interleukin-1's. A neuropeptide-like sequence, flanked by basic dipeptides, was observed within the aFGF sequence.
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Cites
A simple method for displaying the hydropathic character of a protein
Kyte, J., & Doolittle, R. F. (1982) · Journal of Molecular Biology · doi:10.1016/0022-2836(82)90515-0 · Cited by 22,843
Prediction of protein antigenic determinants from amino acid sequences.
Hopp, T. P., & Woods, K. R. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.6.3824 · Cited by 3,705
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
March, C. J., Mosley, B., Larsen, A., Cerretti, D. P., Braedt, G., Price, V., Gillis, S., Henney, C. S., Kronheim, S. R., Grabstein, K., et al. (1985) · Nature · doi:10.1038/315641a0 · Cited by 1,579
Hydrophobicity of Amino Acid Residues in Globular Proteins
Rose, G. D., Geselowitz, A. R., Lesser, G. J., Lee, R. H., & Zehfus, M. H. (1985) · Science · doi:10.1126/science.4023714 · Cited by 1,175
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.
Auron, P. E., Webb, A. C., Rosenwasser, L. J., Mucci, S. F., Rich, A., Wolff, S. M., & Dinarello, C. A. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.24.7907 · Cited by 1,042
Cloning and expression of murine interleukin-1 cDNA in Escherichia coli
Lomedico, P. T., Gubler, U., Hellmann, C. P., Dukovich, M., Giri, J. G., Pan, Y.-C. E., Collier, K., Semionow, R., Chua, A. O., & Mizel, S. B. (1984) · Nature · doi:10.1038/312458a0 · Cited by 816
Esch, F., Baird, A., Ling, N., Ueno, N., Hill, F., Denoroy, L., Klepper, R., Gospodarowicz, D., Böhlen, P., & Guillemin, R. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.19.6507 · Cited by 693
Stimulation of connective tissue cell growth by substance P and substance K
Nilsson, J., von Euler, A. M., & Dalsgaard, C.-J. (1985) · Nature · doi:10.1038/315061a0 · Cited by 679
Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells.
Rozengurt, E., & Sinnett-Smith, J. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.10.2936 · Cited by 464
Correlation of sequence hydrophobicities measures similarity in three-dimensional protein structure
Sweet, R. M., & Eisenberg, D. (1983) · Journal of Molecular Biology · doi:10.1016/0022-2836(83)90041-4 · Cited by 398
Cited by
Folkman, J., & Klagsbrun, M. (1987) · Science · doi:10.1126/science.2432664 · Cited by 3,491
The Fibroblast Growth Factor signaling pathway
Ornitz, D. M., & Itoh, N. (2015) · WIREs Developmental Biology · doi:10.1002/wdev.176 · Cited by 2,050
Trophic factors and neuronal survival
Barde, Y.-A. (1989) · Neuron · doi:10.1016/0896-6273(89)90040-8 · Cited by 1,625
Fibroblast growth factors, their receptors and signaling
Powers, C. J., McLeskey, S. W., & Wellstein, A. (2000) · Endocrine-related cancer · doi:10.1677/erc.0.0070165 · Cited by 1,332
Interleukin 1 of the central nervous system is produced by ameboid microglia.
Giulian, D., Baker, T. J., Shih, L. C., & Lachman, L. B. (1986) · The Journal of experimental medicine · doi:10.1084/jem.164.2.594 · Cited by 859
Metadata
- Authors
- Gimenez-Gallego, G., Rodkey, J., Bennett, C., Rios-Candelore, M., DiSalvo, J., & Thomas, K.
- Venue
- Science
- Published
- 1985-12-20
- Volume
- 230
- Issue
- 4732
- Pages
- 1385-1388
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2007381150
- Cited by
- 329
- References
- 21
- FWCI
- 17.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gimenez-Gallego, G., Rodkey, J., Bennett, C., Rios-Candelore, M., DiSalvo, J., & Thomas, K. (1985). Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies. Science. https://doi.org/10.1126/science.4071057
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
