The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Cholecystokinin Octapeptide: Continuous Picomole Injections Into the Cerebral Ventricles of Sheep Suppress Feeding
Abstract
Cholecystokinin octapeptide decreased food intake in a dose-related manner when injected continuously into the lateral cerebral ventricles of sheep that had been deprived of food for 2, 4, 8, or 24 hours. In sheep deprived of food for 2 hours, as little as 0.01 picomole per minute suppressed feeding 35 percent 1 hour after beginning injection. Pentagastrin also decreased feeding in the 2-hour group, but only at a much higher dose range. Secretin had no effect. These findings support the hypothesis that cholecystokinin octapeptide acts on central nervous system structures that are involved in control of food intake.
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Citations
Cites
Cholecystokinin decreases food intake in rats.
Gibbs, J., Young, R. C., & Smith, G. P. (1973) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0034870 · Cited by 1,491
McDonald, I. W., & Warner, A. C. I. (1975) · Cited by 1,169
Cholecystokinin octapeptide-like immunoreactivity: histochemical localization in rat brain.
Innis, R. B., Corrêa, F. M., Uhl, G. R., Schneider, B., & Snyder, S. H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.521 · Cited by 451
Isolation, structure and biological activity of two cholecystokinin octapeptides from sheep brain
DOCKRAY, G. J., GREGORY, R. A., HUTCHISON, J. B., IEUAN HARRIS, J., & RUNSWICK, M. J. (1978) · Nature · doi:10.1038/274711a0 · Cited by 436
Perfusion of the cerebral ventricular system in unanesthetized goats
Pappenheimer, J. R., Heisey, S. R., Jordan, E. F., & Downer, J. D. (1962) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1962.203.5.763 · Cited by 348
Cholecystokinin and its COOH-terminal octapeptide in the pig brain.
Muller, J. E., Straus, E., & Yalow, R. S. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.7.3035 · Cited by 258
Localisation of gastrins to neuro- and adenohypophysis
Rehfeld, J. F. (1978) · Nature · doi:10.1038/271771a0 · Cited by 246
Straus, E. W., Muller, J. E., Choi, H. S., et al. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.7.3033 · Cited by 129
Ventromedial hypothalamus and short-term feeding suppression by caerulein in male rats.
Stern, J. J., Cudillo, C. A., & Kruper, J. (1976) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077218 · Cited by 112
Radioimmunoassay of cholecystokinin-pancreozymin
Harvey, R. F., Dowsett, L., Hartog, M., & Read, A. E. (1974) · Gut · doi:10.1136/gut.15.9.690 · Cited by 64
Cited by
Hill, J. M., Lesniak, M. A., Pert, C. B., & Roth, J. (1986) · Neuroscience · doi:10.1016/0306-4522(86)90082-5 · Cited by 413
Sakanaka, M., Shibasaki, T., & Lederis, K. (1986) · Brain Research · doi:10.1016/0006-8993(86)91332-6 · Cited by 337
The vagus nerve in thermoregulation and energy metabolism
Székely, M. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00217-4 · Cited by 84
Metadata
- Authors
- Della-Fera, M. A., & Baile, C. A.
- Venue
- Science
- Published
- 1979-10-26
- Volume
- 206
- Issue
- 4417
- Pages
- 471-473
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2017705025
- Cited by
- 337
- References
- 10
- FWCI
- 13.74
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Cholecystokinin Octapeptide: Continuous Picomole Injections Into the Cerebral Ventricles of Sheep Suppress Feeding. https://app.cochat.ai/papers/10.1126/science.504989
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- Della-Fera, M. A., & Baile, C. A. (1979). Cholecystokinin Octapeptide: Continuous Picomole Injections Into the Cerebral Ventricles of Sheep Suppress Feeding. Science. https://doi.org/10.1126/science.504989
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
