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Cholecystokinin and its COOH-terminal octapeptide in the pig brain.
Open accessAbstract
Two components--one resembling intact cholecystokinin in size and charge and immunologic specificity, and the other resembling the COOH-terminal octapeptide of cholecystokinin--have been found in extracts of the pig cerebral cortex. The relative concentrations of the two peptides in the extracts were dependent on the extractant, boiling 0.1 M HCl being more effective than boiling water for the extraction of intact cholecystokinin but less effective for the extraction of the octapeptide. The physiologic role of these peptides in the brain has yet to be elucidated.
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Cited by
Prolactin: structure, function, and regulation of secretion
Freeman, M. E., Kanyicska, B., Lerant, A., & Nagy, G. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.4.1523 · Cited by 2,457
Cholecystokinin octapeptide-like immunoreactivity: histochemical localization in rat brain.
Innis, R. B., Corrêa, F. M., Uhl, G. R., Schneider, B., & Snyder, S. H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.521 · Cited by 451
Della-Fera, M. A., & Baile, C. A. (1979) · Science · doi:10.1126/science.504989 · Cited by 337
Liddle, R. A. (1997) · Annual Review of Physiology · doi:10.1146/annurev.physiol.59.1.221 · Cited by 280
Evidence against extrapancreatic insulin synthesis.
Eng, J., & Yalow, R. S. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.7.4576 · Cited by 66
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Metadata
- Authors
- Muller, J. E., Straus, E., & Yalow, R. S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1977-07
- Volume
- 74
- Issue
- 7
- Pages
- 3035-3037
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2027179830
- Cited by
- 258
- References
- 0
- FWCI
- 7.26
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Cholecystokinin and its COOH-terminal octapeptide in the pig brain. https://app.cochat.ai/papers/10.1073/pnas.74.7.3035
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- Muller, J. E., Straus, E., & Yalow, R. S. (1977). Cholecystokinin and its COOH-terminal octapeptide in the pig brain. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.74.7.3035
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
