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Stress-Induced Eating Is Mediated Through Endogenous Opiates
Abstract
The interaction of endogenous opiates and stress-induced eating in rats was evaluated by pharmacological manipulation. Eating induced by the tail-pinch method was inhibited by the opiate antagonist naloxone; after being repeatedly stressed over a 10-day period and then given naloxone, the rats behaved in a manner indistinguishable from the "wet-dog" shakes of opiate withdrawal. Thus endogenous opiates may have a role in the control of stress-related eating, a finding that may have therapeutic implications for humans.
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Cited by
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Koole, S. L. (2009) · Cognition & Emotion · doi:10.1080/02699930802619031 · Cited by 1,490
Bergasa, N. V., Alling, D. W., Talbot, T. L., Swain, M. G., Yurdaydin, C., Turner, M. L., Schmitt, J. M., Walker, E. C., & Jones, E. A. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-3-199508010-00001 · Cited by 365
Opioid peptides and the control of human ingestive behaviour
Yeomans, M. R., & Gray, R. W. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(02)00041-6 · Cited by 317
Interactions between sucrose, pain and isolation distress
Blass, E., Fitzgerald, E., & Kehoe, P. (1987) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(87)90153-5 · Cited by 294
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Bruijnzeel, A. W. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.09.008 · Cited by 214
Metadata
- Authors
- Morley, J. E., & Levine, A. S.
- Venue
- Science
- Published
- 1980-09-12
- Volume
- 209
- Issue
- 4462
- Pages
- 1259-1261
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2002747090
- Cited by
- 295
- References
- 0
- FWCI
- 11.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- Morley, J. E., & Levine, A. S. (1980). Stress-Induced Eating Is Mediated Through Endogenous Opiates. Science. https://doi.org/10.1126/science.6250222
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