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Cited by 415

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Molecular and Cellular Mechanisms of Leukocyte Chemotaxis

Snyderman, Ralph, Goetzl, Edward J.·1981·Science

Abstract

The application of modern scientific methods to the study of leukocyte function has begun to reveal the molecular and cytostructural bases of the chemotactic responses of these cells. Leukocyte chemotaxis is initiated by the binding of chemoattractants to distinct plasma membrane receptors; this binding alters transmembrane potential and activates ionic fluxes. The subsequent sequence of metabolic processes leads to a rearrangement of cytoskeletal elements that is manifested by orientation and migration of the cells toward the source of the chemotactic gradient.

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Metadata

Authors
Snyderman, R., & Goetzl, E. J.
Venue
Science
Published
1981-08-21
Volume
213
Issue
4510
Pages
830-837
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2012982812
Cited by
415
References
0
FWCI
24.93
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Molecular and Cellular Mechanisms of Leukocyte Chemotaxis. https://app.cochat.ai/papers/10.1126/science.6266014
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Snyderman, R., & Goetzl, E. J. (1981). Molecular and Cellular Mechanisms of Leukocyte Chemotaxis. Science. https://doi.org/10.1126/science.6266014

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.