The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Brain Aging Correlates: Retardation by Hormonal-Pharmacological Treatments
Abstract
Mid-aged rats were either adrenalectomized and chronically maintained, or left intact and treated daily for a 9- to 10-month period with a potent analog of the peptide adrenocorticotropin (residues 4 to 9), which has some stimulant properties, or with the neural stimulant pentylenetetrazole. All three treatments reduced hippocampal morphologic correlates of brain aging (neuronal loss, glial reactivity). The pentylenetetrazole and peptide treatments also improved reversal learning. These results suggest that certain endogenous peptides, with stimulant properties, may also exert long-term, trophic effects on brain structure and function.
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Cites
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Self-citationAlzheimer's disease : senile dementia and related disorders
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Self-citationThe Regulation of Physiological Changes During Mammalian Aging
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McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 5,429
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Brain corticosteroid receptor balance in health and disease
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Metadata
- Authors
- Landfield, P. W., Baskin, R. K., & Pitler, T. A.
- Venue
- Science
- Published
- 1981-10-30
- Volume
- 214
- Issue
- 4520
- Pages
- 581-584
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2033948248
- Cited by
- 521
- References
- 20
- FWCI
- 3.33
- Type
- journal article
- Language
- en
- Open access
- closed
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- Landfield, P. W., Baskin, R. K., & Pitler, T. A. (1981). Brain Aging Correlates: Retardation by Hormonal-Pharmacological Treatments. Science. https://doi.org/10.1126/science.6270791
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
