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The Alu Family of Dispersed Repetitive Sequences
Abstract
A family of related sequences that includes approximately 500,000 members is the most prominent short dispersed repeat family in primate and rodent DNA's. The primate sequence is approximately 300 base pairs in length and is composed of two imperfectly repeated monomer units, whereas the rodent repeat consists of only a single monomer. Properties of this repeat sequence, its flanking sequences in chromosomal DNA, and RNA's transcribed from it suggest that it may be a mobile DNA element inserted at hundreds of thousands of different chromosomal locations.
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Cited by
Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System
Goldstein, J. L., Brown, M. S., Anderson, R. G. W., Russell, D. W., & Schneider, W. J. (1985) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.01.110185.000245 · Cited by 1,600
The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA
Yamamoto, T., Davis, C. G., Brown, M. S., Schneider, W. J., Casey, M. L., Goldstein, J. L., & Russell, D. W. (1984) · Cell · doi:10.1016/0092-8674(84)90188-0 · Cited by 1,382
The mosaic genome of warm-blooded vertebrates
Bernardi, G., Olofsson, B., Filipski, J., Zerial, M., Salinas, J., Cuny, G., Meunier-Rotival, M., & Rodier, F. (1985) · Science · doi:10.1126/science.4001930 · Cited by 875
Carcinoembryonic antigen gene family: Molecular biology and clinical perspectives
Thompson, J. A., Grunert, F., & Zimmermann, W. (1991) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.1860050510 · Cited by 608
Alu sequences are processed 7SL RNA genes
Ullu, E., & Tschudi, C. (1984) · Nature · doi:10.1038/312171a0 · Cited by 608
Metadata
- Authors
- Schmid, C. W., & Jelinek, W. R.
- Venue
- Science
- Published
- 1982-06-04
- Volume
- 216
- Issue
- 4550
- Pages
- 1065-1070
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2013912153
- Cited by
- 597
- References
- 0
- FWCI
- 88.47
- Type
- journal article
- Language
- en
- Open access
- closed
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- Schmid, C. W., & Jelinek, W. R. (1982). The Alu Family of Dispersed Repetitive Sequences. Science. https://doi.org/10.1126/science.6281889
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
