The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Crypts Are the Site of Intestinal Fluid and Electrolyte Secretion
Abstract
The site of adenosine 3′,5′-monophosphate-mediated fluid and electrolyte secretion across mammalian large intestine was found to be the crypts of Lieberkühn by means of two techniques. First, the formation of fluid droplets was visualized on the oil-covered mucosal surface directly over crypt duct openings when secretion was stimulated. Second, microelectrode impalement of individual surface and crypt cells revealed that only the crypt cells produced a pattern of secretagogue-induced alterations in membrane potential and resistance that was characteristic of secretory epithelia.
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Citations
Cites
Ion transport by rabbit colon: I. Active and passive components
Frizzell, R. A., Koch, M. J., & Schultz, S. G. (1976) · The Journal of Membrane Biology · doi:10.1007/bf01869142 · Cited by 331
Self-citationMechanism of rapid mucus secretion in goblet cells stimulated by acetylcholine.
Specian, R. D., & Neutra, M. R. (1980) · The Journal of cell biology · doi:10.1083/jcb.85.3.626 · Cited by 276
Site and mode of adrenaline action on chloride transport across the rabbit corneal epithelium.
Klyce, S. D., & Wong, R. K. (1977) · The Journal of Physiology · doi:10.1113/jphysiol.1977.sp011793 · Cited by 163
Active and passive properties of rabbit descending colon: A microelectrode and nystatin study
Wills, N. K., Lewis, S. A., & Eaton, D. C. (1979) · The Journal of Membrane Biology · doi:10.1007/bf01869296 · Cited by 151
The response of small intestinal villous and crypt epithelium to choleratoxin in rat and guinea pig
JONGE, H. R. D. (1975) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(75)90195-6 · Cited by 67
Field, M., Smith, P. L., & Bolton, J. E. (1980) · The Journal of Membrane Biology · doi:10.1007/bf01869457 · Cited by 61
Self-citation
Cited by
Electrolyte transport in the mammalian colon: mechanisms and implications for disease
Kunzelmann, K., & Mall, M. (2002) · Physiological Reviews · doi:10.1152/physrev.00026.2001 · Cited by 655
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells
Prasad, S., Mingrino, R., Kaukinen, K., Hayes, K. L., Powell, R. M., MacDonald, T. T., & Collins, J. E. (2005) · Laboratory Investigation · doi:10.1038/labinvest.3700316 · Cited by 490
Chloride Secretion by the Intestinal Epithelium: Molecular Basis and Regulatory Aspects
Barrett, K. E., & Keely, S. J. (2000) · Annual Review of Physiology · doi:10.1146/annurev.physiol.62.1.535 · Cited by 489
Troeger, H., Epple, H.-J., Schneider, T., Wahnschaffe, U., Ullrich, R., Burchard, G.-D., Jelinek, T., Zeitz, M., Fromm, M., & Schulzke, J.-D. (2007) · Gut · doi:10.1136/gut.2006.100198 · Cited by 221
Self-citation2 Electrophysiology of Ion Transport in Teleost Intestinal Cells
Loretz, C. A. (1995) · Fish Physiology · doi:10.1016/s1546-5098(08)60241-1 · Cited by 159
Metadata
- Authors
- Welsh, M. J., Smith, P. L., Fromm, M., & Frizzell, R. A.
- Venue
- Science
- Published
- 1982-12-17
- Volume
- 218
- Issue
- 4578
- Pages
- 1219-1221
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1982972448
- Cited by
- 358
- References
- 6
- FWCI
- 5.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- Welsh, M. J., Smith, P. L., Fromm, M., & Frizzell, R. A. (1982). Crypts Are the Site of Intestinal Fluid and Electrolyte Secretion. Science. https://doi.org/10.1126/science.6293054
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
