The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Adoptive Immunotherapy of Established Pulmonary Metastases with LAK Cells and Recombinant Interleukin-2
Abstract
The activation of human peripheral blood leukocytes or murine splenocytes with interleukin-2 (IL-2) generated cells that were lytic in vitro for a variety of fresh tumor cells. The adoptive transfer of such lymphokine-activated killer (LAK) cells to mice with established pulmonary sarcoma metastases was highly effective in reducing the number (and size) of these tumor nodules when combined with repeated injections of recombinant IL-2. These findings provide a rationale for clinical trials of the infusion of human LAK cells generated with recombinant IL-2 as well as Phase I trials of the infusion of recombinant IL-2 systemically into humans.
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Citations
Cites
Grimm, E. A., Mazumder, A., Zhang, H. Z., & Rosenberg, S. A. (1982) · The Journal of experimental medicine · doi:10.1084/jem.155.6.1823 · Cited by 2,204
Self-citationNorth, R. J. (1982) · The Journal of experimental medicine · doi:10.1084/jem.155.4.1063 · Cited by 650
Biological Activity of Recombinant Human Interleukin-2 Produced in Escherichia coli
Rosenberg, S. A., Grimm, E. A., McGrogan, M., Doyle, M., Kawasaki, E., Koths, K., & Mark, D. F. (1984) · Science · doi:10.1126/science.6367046 · Cited by 595
Self-citationLysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor.
Lotze, M. T., Grimm, E. A., Mazumder, A., Strausser, J. L., & Rosenberg, S. A. (1981) · PubMed · Cited by 523
Self-citationAccurate Identification of Experimental Pulmonary Metastases2
Wexler, H. (1966) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/36.4.641 · Cited by 407
The fate of interleukin-2 after in vivo administration.
Donohue, J. H., & Rosenberg, S. A. (1983) · The Journal of Immunology · doi:10.4049/jimmunol.130.5.2203 · Cited by 375
Self-citationMazumder, A., & Rosenberg, S. A. (1984) · The Journal of experimental medicine · doi:10.1084/jem.159.2.495 · Cited by 369
Self-citationRosenstein, M., Yron, I., Kaufmann, Y., & Rosenberg, S. A. (1984) · PubMed · Cited by 297
Self-citationCheever, M. A., Greenberg, P. D., Fefer, A., & Gillis, S. (1982) · The Journal of experimental medicine · doi:10.1084/jem.155.4.968 · Cited by 265
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Cited by
Rosenberg, S. A., Packard, B. S., Aebersold, P. M., Solomon, D., Topalian, S. L., Toy, S. T., Simon, P., Lotze, M. T., Yang, J. C., Seipp, C. A., et al. (1988) · New England Journal of Medicine · doi:10.1056/nejm198812223192527 · Cited by 2,389
Self-citationHibbs, J. B., Westenfelder, C., Taintor, R., Vavrin, Z., Kablitz, C., Baranowski, R. L., Ward, J. H., Menlove, R. L., McMurry, M. P., & Kushner, J. P. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115666 · Cited by 485
Magee, M. S., Abraham, T. S., Baybutt, T. R., Flickinger, J. C., Ridge, N. A., Marszalowicz, G. P., Prajapati, P., Hersperger, A. R., Waldman, S. A., & Snook, A. E. (2018) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-16-0362 · Cited by 143
Large scale production of human lymphokine activated killer cells for use in adoptive immunotherapy
Mesler Muul, L., Director, E. P., Hyatt, C. L., & Rosenberg, S. A. (1986) · Journal of Immunological Methods · doi:10.1016/0022-1759(86)90015-3 · Cited by 82
Self-citation
Metadata
- Authors
- Mulé, J. J., Shu, S., Schwarz, S. L., & Rosenberg, S. A.
- Venue
- Science
- Published
- 1984-09-28
- Volume
- 225
- Issue
- 4669
- Pages
- 1487-1489
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2014113952
- Cited by
- 688
- References
- 12
- FWCI
- 14.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mulé, J. J., Shu, S., Schwarz, S. L., & Rosenberg, S. A. (1984). Adoptive Immunotherapy of Established Pulmonary Metastases with LAK Cells and Recombinant Interleukin-2. Science. https://doi.org/10.1126/science.6332379
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
