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Chromosomal Mosaicism Confined to the Placenta in Human Conceptions

Kalousek, D .K., Dill, F. J.·1983·Science

Abstract

Placental and fetal tissues from 46 human pregnancies were cultured and cytogenetically analyzed in an attempt to document the existence of chromosomal mosaicism confined strictly to tissues of extraembryonic origin. In two gestations in which chromosomal mosaicism was found, it was expressed exclusively in placental chorionic cells and was not detected in cells derived from the embryo proper. This demonstration of confined chorionic mosaicism may have implications for the understanding of the fetoplacental unit and for prenatal diagnosis.

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Metadata

Authors
Kalousek, D. K., & Dill, F. J.
Venue
Science
Published
1983-08-12
Volume
221
Issue
4611
Pages
665-667
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2008478368
Cited by
394
References
0
FWCI
21.19
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Chromosomal Mosaicism Confined to the Placenta in Human Conceptions. https://app.cochat.ai/papers/10.1126/science.6867735
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Kalousek, D. K., & Dill, F. J. (1983). Chromosomal Mosaicism Confined to the Placenta in Human Conceptions. Science. https://doi.org/10.1126/science.6867735

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