The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Cortical Dopaminergic Involvement in Cocaine Reinforcement
Abstract
Neuronal systems involved in the initiation of cocaine reinforcement were investigated by identifying brain sites where direct application of the drug was reinforcing. This was accomplished by allowing rats to self-administer picomolar concentrations of cocaine into discrete brain regions. The medial prefrontal cortex supported self-administration, while the nucleus accumbens and ventral tegmental area did not. Self-administration could be attenuated by including equimolar concentrations of the dopaminergic D 2 -receptor antagonist sulpiride in the microinjection system. These results imply that cocaine reinforcement is mediated in part through a direct action on mesocortical dopaminergic receptors.
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de Wit, H., & Wise, R. A. (1977) · Canadian Journal of Psychology / Revue canadienne de psychologie · doi:10.1037/h0081662 · Cited by 491
Cited by
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Wise, R. A., & Bozarth, M. A. (1987) · Psychological Review · doi:10.1037/0033-295x.94.4.469 · Cited by 2,747
Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine
Ritz, M. C., Lamb, R. J., Goldberg, S. R., & Kuhar, M. J. (1987) · Science · doi:10.1126/science.2820058 · Cited by 2,180
Cellular and molecular mechanisms of drug dependence
Koob, G. F., & Bloom, F. E. (1988) · Science · doi:10.1126/science.2903550 · Cited by 2,070
Jentsch, J. D., & Taylor, J. R. (1999) · Psychopharmacology · doi:10.1007/pl00005483 · Cited by 1,545
Metadata
- Authors
- Goeders, N. E., & Smith, J. E.
- Venue
- Science
- Published
- 1983-08-19
- Volume
- 221
- Issue
- 4612
- Pages
- 773-775
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2030078771
- Cited by
- 488
- References
- 1
- FWCI
- 4.13
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
