The DOI matches its Crossref record.
Two Coronaviruses Isolated from Central Nervous System Tissue of Two Multiple Sclerosis Patients
Abstract
Two coronaviruses were isolated from brain material obtained at autopsy from two multiple sclerosis patients. The viruses were neutralized by serum and spinal fluid from these patients. Although most of the population have antibody to these virus isolates, multiple sclerosis patients have slightly higher concentrations of serum antibody than controls. The results suggest that coronaviruses should be considered as one additional virus with a potential implication in the etiology of multiple sclerosis.
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Citations
Cited by
Coronavirus Pathogenesis and the Emerging Pathogen Severe Acute Respiratory Syndrome Coronavirus
Weiss, S. R., & Navas-Martin, S. (2005) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.69.4.635-664.2005 · Cited by 1,256
Neurologic alterations due to respiratory virus infections
Bohmwald, K., Gálvez, N. M. S., Ríos, M., & Kalergis, A. M. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00386 · Cited by 636
“Despite HCoV capacities to infect CNS, it has been recently characterized, its presence in human CNS-related samples date back as early as 1980, where the first detection of this virus was performed in autopsy of patients with MS (Burks et al., 1980).”
BackgroundCollins, A. R., Knobler, R. L., Powell, H., & Buchmeier, M. J. (1982) · Virology · doi:10.1016/0042-6822(82)90095-2 · Cited by 317
Experimental models of virus-induced demyelination of the central nervous system
Dal Canto, M. C., & Rabinowitz, S. G. (1982) · Annals of Neurology · doi:10.1002/ana.410110202 · Cited by 173
“Furthermore, coronaviruses have been isolated from the brains of two MS patients [9] .”
BackgroundMontero-Escribano, P., Matías-Guiu, J., Gómez-Iglesias, P., Porta-Etessam, J., Pytel, V., & Matias-Guiu, J. A. (2020) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2020.102185 · Cited by 128
Metadata
- Authors
- Burks, J. S., DeVald, B. L., Jankovsky, L. D., & Gerdes, J. C.
- Venue
- Science
- Published
- 1980-08-22
- Volume
- 209
- Issue
- 4459
- Pages
- 933-934
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1987936529
- Cited by
- 234
- References
- 0
- FWCI
- 9.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Two Coronaviruses Isolated from Central Nervous System Tissue of Two Multiple Sclerosis Patients. https://app.cochat.ai/papers/10.1126/science.7403860
- The paper
- Burks, J. S., DeVald, B. L., Jankovsky, L. D., & Gerdes, J. C. (1980). Two Coronaviruses Isolated from Central Nervous System Tissue of Two Multiple Sclerosis Patients. Science. https://doi.org/10.1126/science.7403860
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
