The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Hormone Accumulation in a Sexually Dimorphic Motor Nucleus of the Rat Spinal Cord
Abstract
The fifth and sixth lumbar segments of the rat spinal cord were found to contain a sexually dimorphic nucleus, the spinal nucleus of the bulbocavernosus (SNB). The SNB, which contains motoneurons innervating perineal striated muscles in normal male rats, is diminished or absent in normal females and in males with a genetic mutation rendering them insensitive to androgens. The presence of the nucleus is apparently not dependent on genetic sex, but on the action of androgens. The motoneurons of the adult male SNB accumulate hormone after systemic injections of radioactive testosterone or dihydrotestosterone, but not estradiol, and the SNB motoneurons accumulate more of the injected androgens than do other motoneurons in the same spinal segments. These results demonstrate a morphological sex difference in hormone-sensitive motoneurons that are probably involved in the sexually dimorphic copulatory behavior of the rat.
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Citations
Cites
Estimation of nuclear population from microtome sections
Abercrombie, M. (1946) · The Anatomical Record · doi:10.1002/ar.1090940210 · Cited by 4,363
Cited by
Simerly, R. B., Swanson, L. W., Chang, C., & Muramatsu, M. (1990) · Journal of Comparative Neurology · doi:10.1002/cne.902940107 · Cited by 2,118
Gonadal Steroid Induction of Structural Sex Differences in the Central Nervous System
Arnold, A. P., & Gorski, R. A. (1984) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.07.030184.002213 · Cited by 1,198
Self-citationSexual differentiation of the vertebrate nervous system
Morris, J. A., Jordan, C. L., & Breedlove, S. M. (2004) · Nature Neuroscience · doi:10.1038/nn1325 · Cited by 627
Self-citationArnold, A. P. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.03.011 · Cited by 625
Self-citationMinireview: sex differences in adult and developing brains: compensation, compensation, compensation
De Vries, G. J. (2004) · Endocrinology · doi:10.1210/en.2003-1504 · Cited by 486
Metadata
- Authors
- Breedlove, S. M., & Arnold, A. P.
- Venue
- Science
- Published
- 1980-10-31
- Volume
- 210
- Issue
- 4469
- Pages
- 564-566
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1995114201
- Cited by
- 594
- References
- 1
- FWCI
- 8.37
- Type
- journal article
- Language
- en
- Open access
- closed
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- Breedlove, S. M., & Arnold, A. P. (1980). Hormone Accumulation in a Sexually Dimorphic Motor Nucleus of the Rat Spinal Cord. Science. https://doi.org/10.1126/science.7423210
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