The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Relation of Mammalian Sperm Chromatin Heterogeneity to Fertility
Abstract
Flow cytometry of heated sperm nuclei revealed a significant decrease in resistance to in situ denaturation of spermatozoal DNA in samples from bulls, mice, and humans of low or questionable fertility when compared with others of high fertility. Since thermal denaturation of DNA in situ depends on chromatin structure, it is assumed that changes in sperm chromatin conformation may be related to the diminished fertility. Flow cytometry of heated sperm nuclei may provide a new and independent determinant of male fertility.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Human zinc deficiency, endocrine manifestations and response to treatment
SANDSTEAD, H. H., PRASAD, A. S., SCHULERT, A. R., FARID, Z., MIALE, A., BASSILLY, S., & DARBY, W. J. (1967) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/20.5.422 · Cited by 388
Cited by
Evenson, D. P. (1999) · Human Reproduction · doi:10.1093/humrep/14.4.1039 · Cited by 1,121
Self-citationEVENSON, D. P., LARSON, K. L., & JOST, L. K. (2002) · Journal of Andrology · doi:10.1002/j.1939-4640.2002.tb02599.x · Cited by 1,072
Self-citationOllero, M., Gil-Guzman, E., Lopez, M. C., Sharma, R. K., Agarwal, A., Larson, K., Evenson, D., Thomas, A. J., & Alvarez, J. G. (2001) · Human Reproduction · doi:10.1093/humrep/16.9.1912 · Cited by 392
Self-citationSperm chromatin structure and male fertility: biological and clinical aspects
Erenpreiss, J., Spano, M., Erenpreisa, J., Bungum, M., & Giwercman, A. (2006) · Asian Journal of Andrology · doi:10.1111/j.1745-7262.2006.00112.x · Cited by 304
Should we evaluate and treat sperm DNA fragmentation?
Agarwal, A., Cho, C.-L., & Esteves, S. C. (2016) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000271 · Cited by 148
Metadata
- Authors
- Evenson, D. P., Darzynkiewicz, Z., & Melamed, M. R.
- Venue
- Science
- Published
- 1980-12-05
- Volume
- 210
- Issue
- 4474
- Pages
- 1131-1133
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2036183167
- Cited by
- 812
- References
- 1
- FWCI
- 3.15
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Relation of Mammalian Sperm Chromatin Heterogeneity to Fertility. https://app.cochat.ai/papers/10.1126/science.7444440
- The paper
- Evenson, D. P., Darzynkiewicz, Z., & Melamed, M. R. (1980). Relation of Mammalian Sperm Chromatin Heterogeneity to Fertility. Science. https://doi.org/10.1126/science.7444440
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
