The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.
Mechanisms of DNA Excision Repair
Abstract
DNA is constantly suffering damage, which ultimately causes 80 to 90 percent of human cancers (1). Usually, cells eliminate DNA lesions by molecular DNA repair, a process first described in 1949 by Kelner (2), who found that risible light protected microorganisms from the lethal effects of ultraviolet (UV) radiation. In 1958 Rupert and co-workers (3) showed that this phenomenon, called photoreactivation, was catalyzed by an enzyme, photoreactivating enzyme (DNA photolyase). Photolyase reverses the major UV-caused lesions in DNA, pyrimidine dimers, by converting light energy into chemical energy (4). Photolvase, however, is not essential for species survival, as many species including humans lack the enzyme (5). In contrast, another DNA repair mechanism, excision repair, which was discovered
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Cites
Oxidants, antioxidants, and the degenerative diseases of aging.
Ames, B. N., Shigenaga, M. K., & Hagen, T. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.7915 · Cited by 5,958
The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today
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Kastan, M. B., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., & Fornace, A. J. (1992) · Cell · doi:10.1016/0092-8674(92)90593-2 · Cited by 3,047
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
Lowe, S. W., Ruley, H. E., Jacks, T., & Housman, D. E. (1993) · Cell · doi:10.1016/0092-8674(93)90719-7 · Cited by 2,925
Defective repair replication of DNA in xeroderma pigmentosum
CLEAVER, J. E. (1968) · Nature · doi:10.1038/218652a0 · Cited by 1,729
THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM
Setlow, R. B., & Carrier, W. L. (1964) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.51.2.226 · Cited by 982
Interaction of the p53-Regulated Protein Gadd45 with Proliferating Cell Nuclear Antigen
Smith, M. L., Chen, I.-T., Zhan, Q., Bae, I., Chen, C.-Y., Gilmer, T. M., Kastan, M. B., O'Connor, P. M., & Fornace, A. J. (1994) · Science · doi:10.1126/science.7973727 · Cited by 944
Proliferating cell nuclear antigen is required for DNA excision repair
Shivji, M. K. K., Kenny, M. K., & Wood, R. D. (1992) · Cell · doi:10.1016/0092-8674(92)90416-a · Cited by 798
DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor
Schaeffer, L., Roy, R., Humbert, S., Moncollin, V., Vermeulen, W., Hoeijmakers, J. H. J., Chambon, P., & Egly, J.-M. (1993) · Science · doi:10.1126/science.8465201 · Cited by 794
Cited by
Cisplatin: mode of cytotoxic action and molecular basis of resistance
Siddik, Z. H. (2003) · Oncogene · doi:10.1038/sj.onc.1206933 · Cited by 3,335
Role of oxygen free radicals in cancer development
Dreher, D., & Junod, A. F. (1996) · European Journal of Cancer · doi:10.1016/0959-8049(95)00531-5 · Cited by 855
DNA DAMAGE AND REPAIR IN PLANTS
Britt, A. B. (1996) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.47.1.75 · Cited by 486
Vries, A. D., van Oostrom, C. T. M., Hofhuis, F. M. A., Dortant, P. M., Berg, R. J. W., Gruijl, F. R. D., Wester, P. W., van Kreijl, C. F., Capel, P. J. A., Steeg, H. V., et al. (1995) · Nature · doi:10.1038/377169a0 · Cited by 406
Prokaryotic Nucleotide Excision Repair: The UvrABC System
Truglio, J. J., Croteau, D. L., Van Houten, B., & Kisker, C. (2006) · Chemical Reviews · doi:10.1021/cr040471u · Cited by 340
Metadata
- Authors
- Sancar, A.
- Venue
- Science
- Published
- 1994-12-23
- Volume
- 266
- Issue
- 5193
- Pages
- 1954-1956
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2049601212
- Cited by
- 555
- References
- 75
- FWCI
- 19.49
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
