The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Binding and Stimulation of HIV-1 Integrase by a Human Homolog of Yeast Transcription Factor SNF5
Abstract
Upon entry into a host cell, retroviruses direct the reverse transcription of the viral RNA genome and the establishment of an integrated proviral DNA. The retroviral integrase protein (IN) is responsible for the insertion of the viral DNA into host chromosomal targets. The two-hybrid system was used to identify a human gene product that binds tightly to the human immunodeficiency virus-type 1 (HIV-1) integrase in vitro and stimulates its DNA-joining activity. The sequence of the gene suggests that the protein is a human homolog of yeast SNF5, a transcriptional activator required for high-level expression of many genes. The gene, termed INI1 (for integrase interactor 1), may encode a nuclear factor that promotes integration and targets incoming viral DNA to active genes.
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Cites
A novel genetic system to detect protein–protein interactions
Fields, S., & Song, O.-K. (1989) · Nature · doi:10.1038/340245a0 · Cited by 6,114
Smith, D. B., & Johnson, K. S. (1988) · Gene · doi:10.1016/0378-1119(88)90005-4 · Cited by 5,892
Structural features in eukaryotic mRNAs that modulate the initiation of translation.
Kozak, M. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54860-2 · Cited by 1,836
Tissue-specific in vitro transcription from the mouse albumin promoter
Gorski, K., Carneiro, M., & Schibler, U. (1986) · Cell · doi:10.1016/0092-8674(86)90519-2 · Cited by 1,253
Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex
Côté, J., Quinn, J., Workman, J. L., & Peterson, C. L. (1994) · Science · doi:10.1126/science.8016655 · Cited by 861
Weiss, R. A., & Bernstein, A. (1982) · Cold Spring Harbor Laboratory eBooks · Cited by 828
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B
Luban, J., Bossolt, K. L., Franke, E. K., Kalpana, G. V., & Goff, S. P. (1993) · Cell · doi:10.1016/0092-8674(93)90637-6 · Cited by 802
Self-citationNucleosome disruption and enhancement of activator binding by a human SW1/SNF complex
Kwon, H., Imbalzano, A. N., Khavari, P. A., Kingston, R. E., & Green, M. R. (1994) · Nature · doi:10.1038/370477a0 · Cited by 779
Khavari, P. A., Peterson, C. L., Tamkun, J. W., Mendel, D. B., & Crabtree, G. R. (1993) · Nature · doi:10.1038/366170a0 · Cited by 669
Self-citationPeterson, C. L., & Herskowitz, I. (1992) · Cell · doi:10.1016/0092-8674(92)90192-f · Cited by 595
Cited by
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
Jordan, A., Bisgrove, D., & Verdin, E. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg188 · Cited by 914
Zhao, K., Wang, W., Rando, O. J., Xue, Y., Swiderek, K., Kuo, A., & Crabtree, G. R. (1998) · Cell · doi:10.1016/s0092-8674(00)81633-5 · Cited by 716
Self-citationHIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells
Cherepanov, P., Maertens, G., Proost, P., Devreese, B., Van Beeumen, J., Engelborghs, Y., De Clercq, E., & Debyser, Z. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209278200 · Cited by 704
Diversity and specialization of mammalian SWI/SNF complexes.
Wang, W., Xue, Y., Zhou, S., Kuo, A., Cairns, B. R., & Crabtree, G. R. (1996) · Genes & Development · doi:10.1101/gad.10.17.2117 · Cited by 707
Self-citationRSC, an Essential, Abundant Chromatin-Remodeling Complex
Cairns, B. R., Lorch, Y., Li, Y., Zhang, M., Lacomis, L., Erdjument-Bromage, H., Tempst, P., Du, J., Laurent, B., & Kornberg, R. D. (1996) · Cell · doi:10.1016/s0092-8674(00)81820-6 · Cited by 675
Metadata
- Authors
- Kalpana, G. V., Marmon, S., Wang, W., Crabtree, G. R., & Goff, S. P.
- Venue
- Science
- Published
- 1994-12-23
- Volume
- 266
- Issue
- 5193
- Pages
- 2002-2006
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2090699693
- Cited by
- 530
- References
- 39
- FWCI
- 6.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kalpana, G. V., Marmon, S., Wang, W., Crabtree, G. R., & Goff, S. P. (1994). Binding and Stimulation of HIV-1 Integrase by a Human Homolog of Yeast Transcription Factor SNF5. Science. https://doi.org/10.1126/science.7801128
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
